Buscar
Mostrando ítems 31-40 de 2178
Involvement of A2B adenosine receptors as anti-inflammatory in gestational diabesity.
(2019)
Pregnant women that are obese may develop gestational diabetes mellitus (GDM) configuring a new metabolic condition referred to as gestational diabesity. The metabolic alterations seen in gestational diabesity include a ...
Increased Gi protein signaling potentiates the negative chronotropic effect of adenosine in the SHR right atrium
(Springer, 2018)
Hypertension is a risk factor for cardiovascular diseases, which have been associated with dysfunction of sympathetic and purinergic neurotransmission. Therefore, herein, we evaluated whether modifications of adenosine ...
Fructose-1,6-bisphosphate reduces inflammatory pain-like behaviour in mice: role of adenosine acting on A(1) receptors
(WILEY-BLACKWELL PUBLISHING, INC, 2009)
Background and purpose: D-Fructose-1,6-bisphosphate (FBP) is an intermediate in the glycolytic pathway, exerting pharmacological actions on inflammation by inhibiting cytokine production or interfering with adenosine ...
Extracellular nucleotide metabolism in Leishmania: influence of adenosine in the establishment of infection
(Microbes and Infection, 2019)
Activation of Adenylyl Cyclase Causes Stimulation of Adenosine Receptors
(Karger, 2018-05)
AbstractBACKGROUND/AIMS:Signaling of Gs protein-coupled receptors (GsPCRs) is accomplished by stimulation of adenylyl cyclase, causing an increase of the intracellular cAMP concentration, activation of the intracellular ...
Extracellular adenosine promotes cell migration/invasion of Glioblastoma Stem-like Cells through A 3 Adenosine Receptor activation under hypoxia
(Elsevier Ireland Ltd, 2019)
Glioblastoma (GBM) is the brain tumor with the worst prognosis composed of a cell subpopulation called Glioblastoma Stem-like Cells (GSCs) responsible for tumor recurrence mediated by cell invasion. GSCs persist in a hypoxic ...
Adenosine modulates alpha2-adrenergic receptors through a phospholipase C pathway in brainstem cell culture of rats
(ELSEVIER SCIENCE BV, 2009)
Adenosine acts in the nucleus tractus solitarii (NTS), one of the main brain sites related to cardiovascular control. In the present study we show that A(1) adenosine receptor (A(1R)) activation promotes an increase on ...
Adenosine actions are preserved in corpus cavernosum from obese and type II diabetic db/db mouse
(BLACKWELL PUBLISHING, 2008)
Introduction. Erectile dysfunction (ED) in diabetes is associated with autonomic neuropathy and endothelial dysfunction. Whereas the nonadrenergic-noncholinergic (NANC)/neurogenic nitric oxide pathway has received great ...
Role of insulin, adenosine, and adipokine receptors in the foetoplacental vascular dysfunction in gestational diabetes mellitus
(2019)
Gestational diabetes mellitus (GDM) is a disease of pregnancy associated with maternal and foetal hyperglycaemia and altered foetoplacental vascular function. Human foetoplacental microvascular and macrovascular endothelium ...