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A pilot, randomized, controlled clinical trial of lucinactant, a peptide-containing synthetic surfactant, in infants with acute hypoxemic respiratory failure
(Lippincott Williams & Wilkins, 2012)
OBJECTIVE:
Inhibition of surfactant function and abnormal surfactant synthesis lead to surfactant dysfunction in children with acute hypoxemic respiratory failure. We evaluated whether intratracheal lucinactant, a synthetic, ...
A pilot, randomized, controlled clinical trial of lucinactant, a peptide-containing synthetic surfactant, in infants with acute hypoxemic respiratory failure
(Lippincott Williams & Wilkins, 2012)
OBJECTIVE:
Inhibition of surfactant function and abnormal surfactant synthesis lead to surfactant dysfunction in children with acute hypoxemic respiratory failure. We evaluated whether intratracheal lucinactant, a synthetic, ...
Development of novel polymer-protein conjugates and characterization of chromatographic supports
(Instituto Tecnológico y de Estudios Superiores de Monterrey, 2021-06-10)
Protein versatility has positioned them as a high-value biotechnological product. Among protein applications, its use as a therapeutic agent is highlighted. However, some therapeutic proteins need a modification process ...
Immunogenicity in protein and peptide based-therapeutics: An overview
(Current Protein and Peptide Science, 2017-08)
Currently it is well known that all biological drugs, including those with a fully human structure, are capable of inducing a host immune response known as immunogenicity [1]. The presence of ADAs can condition the drug´s ...
Exploring the potential for recombinant protein production in microalgaeExploring the potential for recombinant protein productión in microalgae
(2014)
Microalgae are considered as attractive platforms for the synthesis of high-value heterologous proteins due to their many beneficial attributes including ease of cultivation, lack of pathogenic agents, and low-cost downstream ...
Inteins in pathogenic fungi: a phylogenetic tool and perspectives for therapeutic applications
(Instituto Oswaldo Cruz, Ministério da Saúde, 2014)