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TGF-β receptor type II costameric localization in cardiomyocytes and host cell TGF-β response is disrupted by Trypanosoma cruzi infection
(Cambridge University Press, 2016)
Effect of transforming growth factor beta (TGF-β) receptor I kinase inhibitor on prostate cancer bone growth
(Elsevier Science Inc, 2012-03)
Transforming growth factor beta 1 (TGF-β1) has been implicated in the pathogenesis of prostate cancer (PCa) bone metastasis. In this study, we tested the antitumor efficacy of a selective TGF-β receptor I kinase inhibitor, ...
A phosphoproteomic approach towards the understanding of the role of TGF-β in Trypanosoma cruzi biology
(Public Library of Science, 2017)
Role of FoxO3a as a negative regulator of the cardiac myofibroblast conversion induced by TGF-β1
(Elsevier, 2020)
Cardiac fibroblasts (CFs) are necessary to maintain extracellular matrix (ECM) homeostasis in the heart. Normally, CFs are quiescent and secrete small amounts of ECM components, whereas, in pathological conditions, they ...
Participación de miembros de la superfamilia TGF-beta en la patogenia de la enfermedad quística ovárica bovina
(2013-07-04)
El objetivo fue evaluar la localización y expresión ovárica de miembros de la superfamilia TGF-β que podrían participar en la patogenia de la enfermedad quística ovárica bovina. Se muestrearon tres tipos de animales: ...
Anti-fibrotic effect of mycophenolate mofetil on Peyronie’s disease experimentally induced with TGF-β
(2019-01-01)
The aim of the present study was to evaluate the histological, histochemical, and stereological changes caused by mycophenolate mofetil (MMF) on the tunica albuginea of rat penises submitted to an injection of transforming ...
Inhibition of Epithelial-Mesenchymal Transition and Metastasis by Combined TGFbeta Knockdown and Metformin Treatment in a Canine Mammary Cancer Xenograft Model
(2017-03-01)
Epithelial mesenchymal transition (EMT) is a process by which epithelial cells acquire mesenchymal properties, generating metastases. Transforming growth factor beta (TGF-β) is associated with this malignancy by having the ...