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Effects of growth hormone on insulin signal transduction in rat adipose tissue maintained in vitro
(Marcel Dekker IncNew YorkEUA, 2004)
New Interaction Partners For Nek4.1 And Nek4.2 Isoforms: From The Dna Damage Response To Rna Splicing
(BIOMED CENTRAL LTDLONDON, 2015)
Autophosphorylation of carboxy-terminal residues inhibits the activity of protein kinase CK1α
(2009)
CK1 constitutes a protein kinase subfamily that is involved in many important physiological processes. However, there is limited knowledge about mechanisms that regulate their activity. Isoforms CK1δ and CKlε were previously ...
Critical analysis of graft loss and death in kidney transplant recipients treated with mTOR inhibitors
(Sociedade Brasileira de Nefrologia, 2017-03-01)
Abstract Registry studies and systematic reviews have shown higher risk for mortality and graft loss in patients in use of mTOR inhibitors (mTORi) compared to calcineurin-based (CNI) immunosuppressive regimens. The majority ...
Synthesis and preliminary structure-activity relationship study of 2-aryl-2 H -pyrazolo[4,3- c ]quinolin-3-ones as potential checkpoint kinase 1 (Chk1) inhibitors
(Taylor & Francis Ltd, 2017-12)
The serine-threonine checkpoint kinase 1 (Chk1) plays a critical role in the cell cycle arrest in response to DNA damage. In the last decade, Chk1 inhibitors have emerged as a novel therapeutic strategy to potentiate the ...