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Novel Medical Therapies for Pituitary Tumors
(Karger, 2010-07)
Despite considerable progress, there is still no medical treatment available for some kinds of pituitary tumors, in particular hormone inactive adenomas and corticotroph pituitary tumors. Surgical removal or at least ...
GH overexpression causes muscle hypertrophy independent from local IGF-I in a zebrafish transgenic model
(Springer, 2011-06-01)
The aim of the present study was to analyse the morphology of white skeletal muscle in males and females from the GH-transgenic zebrafish (Danio rerio) lineage F0104, comparing the expression of genes related to the ...
Association between IGF-I, IGF-IR and GHRH gene polymorphisms and growth and carcass traits in beef cattle
(Elsevier B.V., 2005-07-01)
Molecular biology techniques are of help in genetic improvement since they permit the identification, mapping and analysis of polymorphisms of genes encoding proteins that act on metabolic pathways involved in economically ...
GH overexpression causes muscle hypertrophy independent from local IGF-I in a zebrafish transgenic model
(Springer, 2011-06-01)
The aim of the present study was to analyse the morphology of white skeletal muscle in males and females from the GH-transgenic zebrafish (Danio rerio) lineage F0104, comparing the expression of genes related to the ...
Expression of neurotensin and its receptors in pituitary adenomas
(WILEY-BLACKWELL, 2008)
The neurotensin (NT) produced in the hypothalamus and in pituitary gonadotrophs and thyrotrophs participates in neuroendocrine regulation. Recently, the involvement of this peptide in normal and neoplastic cell proliferation ...
T3 acutely increases GH mRNA translation rate and GH secretion in hypothyroid rats
(ELSEVIER IRELAND LTD, 2010)
Cytoskeleton controls the stability of transcripts, by mechanisms that involve mRNAs and eEF1A attachment to it. Besides, it plays a key role in protein synthesis and secretion, which seems to be impaired in somatotrophs ...
Orexin and neuropeptide Y: Tissue specific expression and immunoreactivity in the hypothalamus and preoptic area of the cichlid fish Cichlasoma dimerus
(Elsevier, 2013-12)
Neuropeptide Y (NPY) and orexin are neuropeptides involved in the regulation of feeding in vertebrates. In this study we determined the NPY and orexin mRNA tissue expression and their immunoreactivity distribution in both ...
Familial combined pituitary hormone deficiency due to a novel mutation R99Q in the hot spot region of prophet of Pit-1 presenting as constitutional growth delay
(Endocrine Soc, 2003-01-01)
Combined pituitary hormone deficiency (CPHD) is characterized by impaired production of GH and one or more of the other anterior pituitary hormones. Prophet of Pit-1 (PROP-1), one of the pituitary specific homeodomain ...