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Rapid quantification of neuraminidase inhibitor drug resistance in influenza virus quasispecies
(International Medical Press, 2018)
A beginner’s guide for FMDV quasispecies analysis: sub-consensus variant detection and haplotype reconstruction using next-generation sequencing
(Oxford Academic Press, 2020-09)
Deep sequencing of viral genomes is a powerful tool to study RNA virus complexity. However, the analysis of next-generation sequencing data might be challenging for researchers who have never approached the study of viral ...
The honeybee (Apis mellifera) developmental state shapes the genetic composition of the deformed wing virus-A quasispecies during serial transmission
(Springer NatureReindo Unido, 2020-04-06)
The main biological threat to the western honeybee (Apis mellifera) is the parasitic mite Varroa destructor, largely because it vectors lethal epidemics of honeybee viruses that, in the absence of this mite, are relatively ...
Simulação computacional e análise de um modelo fenotípico de evolução viral
(Universidade Federal de São Paulo (UNIFESP), 2011-01-26)
A large amount of viruses of medical importance such as HIV, respiratory syncytial virus, the hepatitis C virus, influenza A (H1N1) and polio virus, has RNA genome. These viruses exhibit extremely high mutational rate, ...
Estudo das quasispécies de HIV-1 no contexto da terapia antirretroviral iniciada durante a infecção aguda e da terapia de resgate com maraviroque
(2019)
A recomendação atual do Ministério da Saúde do Brasil é oferecer a terapia antirretroviral combinada (cART) para todos os indivíduos infectados pelo HIV-1 assim que diagnosticados, independente de seu status imunológico ...
Simulação computacional e análise de um modelo de recombinação retroviral
(Universidade Federal de São Paulo (UNIFESP), 2017-04-28)
Retroviruses cause major diseases in humans, such as Acquired Human Immunodeficiency Syndrome (AIDS), caused by HIV-1, which accounts for 2.1 million new cases in 2015 alone, and T-cell lymphoma, caused by HTLV-1. One of ...
Pirossequenciamento de alta cobertura da região hipervariável 1 do Vírus da Hepatite C
(Universidade Estadual Paulista (Unesp), 2014-04-30)
Hepatitis C is a major public health problem. New HCV antiviral drugs were released on market on 2010; however, excluding for genotype 1, the most used therapy used currently is still based on Interferon (IFN) and Ribavirin. ...