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Tn5AraOut mutagenesis for the identification of Yersinia pestis genes involved in resistance towards cationic antimicrobial peptides
(Elsevier, 2011-05)
Bacterial pathogens display a variety of protection mechanisms against the inhibitory and lethal effects of host cationic antimicrobial peptides (CAMPs). To identify Yersinia pestis genes involved in CAMP resistance, ...
Influência dos Métodos de Sensibilidade aos Antimicrobianos no Uso Clínico das Polimixinas
(Universidade Federal de São Paulo (UNIFESP), 2010-05-04)
Introduction: Acinetobacter spp. e Pseudomonas aeruginosa are important pathogens that cause infections in Brazilian hospitals and have become resistant to almost every available antimicrobial. Thereby, the clinical ...
Nephrotoxicity Of Polymyxin B: Experimental Study In Cells And Implications For Nursing Practice
(Universidade de São Paulo, Escola de Enfermagem, 2014-04-01)
The aim of the study was to characterize the cell damage mechanisms involved in the pathophysiology of cytotoxicity of polymyxin B in proximal tubular cells (LLC - PK1) and discuss about the nurses interventions to identify ...
Emergence of polymyxin B-resistant Acinetobacter baumannii in hospitals in Rio de JaneiroEmergência de Acinetobacter baumannii resistente a polimixina B em hospitais do Rio de Janeiro
(Sociedade Brasileira de Patologia Clínica, 2016)
Polymyxin B as inhibitor of LPS contamination of Schistosoma mansoni recombinant proteins in human cytokine analysis
(Microbial Cell Factories, 2007)
Background: Recombinant proteins expressed in Escherichia coli vectors are generally
contaminated with endotoxin. In this study, we evaluated the ability of Polymyxin B to neutralize
the effect of LPS present as contaminant ...
The challenge of multidrug resistance: The treatment of gram-negative rod infections
(LIPPINCOTT WILLIAMS & WILKINS, 2008)
Infections caused by multidrug-resistant gram-negative bacteria are an increasing problem worldwide. Treatment of these microorganisms is a challenge because resistance limits dramatically therapeutic options. In this ...
Trend analysis of carbapenem-resistant Gram-negative bacteria and antimicrobial consumption in the post-COVID-19 era: an extra challenge for healthcare institutions
(2022-02-01)
The incidence density trend of the carbapenem-resistant Gram-negative bacteria was analysed in device-associated infections and antimicrobial consumption in 99 critical care facilities in a low/middle-income country, between ...
In vitro evaluation of the action of irrigating solutions associated with intracanal medications on Escherichia coli and its endotoxin in root canals
(2011-01-01)
Objective: The purpose of this study was to evaluate the efficacy of auxiliary chemical substances and intracanal medications on Escherichia coli and its endotoxin in root canals. Material and Methods: Teeth were contaminated ...