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Implicaciones farmacológicas de los receptores activados por los proliferadores de peroxisomasPharmacologic implications of Peroxisome proliferator activated Receptors (PPAR)
(Universidad de Antioquia, Facultad de MedicinaMedellín, Colombia, 2021)
Molecular properties of fatty acids related to PPAR binding and metabolic diseases
(SpringerBasel, 2013-07)
Peroxisome proliferator-activated receptor (PPAR) is a class of nuclear receptors responsible for the transcription of genes that regulate the metabolism of carbohydrates and lipids. The main endogenous ligands of PPARs ...
Effects of strength training on osteogenic differentiation and bone strength in aging female Wistar rats
(2017-02-17)
The effects of strength training (ST) on the mechanical bone strength and osteogenic differentiation of bone marrow mesenchymal stromal cells (BMSCs) from adult, aged and exercised aged rats were determined. The exercised ...
Epigenetics of Insulin Resistance: An Emerging Field in Translational Medicine
(Springer, 2013-04)
In this article, we review the current knowledge of and recent insights into the role of epigenetic factors in the development of insulin resistance (IR), with emphasis on peroxisome proliferator-activated receptor gamma ...
Fenofibrate Decreases Ethanol-Induced Neuroinflammation and Oxidative Stress and Reduces Alcohol Relapse in Rats by a PPAR-α-Dependent Mechanism
(Multidisciplinary Digital Publishing Institute (MDPI), 2024)
Elafibranor for the treatment of NAFLD: One pill, two molecular targets and multiple effects in a complex phenotype
(Mexican Association of Hepatology, 2016-05)
Article commented: Elafibranor, an Agonist of the Peroxisome Proliferator-Activated Receptor-α and -δ, Induces Resolution of Nonalcoholic Steatohepatitis Without Fibrosis Worsening.
Time-dependent effects of systemic lipopolysaccharide injection on regulators of antioxidant defense Nrf2 and PGC-1alpha in neonatal rat brain.
(Karger, 2013-04)
Background/Aims: Both excitotoxicity and neuroinflammation are associated with oxidative stress. One transcription factor, nuclear factor E2-related factor 2 (Nrf2), and one transcription cofactor, peroxisome proliferato ...