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Modelo in vitro para el estudio del papel de la unión mesopontina en la generación del sueño de movimientos oculares rápidos y la vigilia
(Udelar. FM., 2017)
El estudio de las estrategias neurales para la organización del comportamiento en vertebrados constituye un desafío mayor para la Neurociencia. El avance del conocimiento en este campo depende de manera crítica de la ...
Nicotine modulates the long-lasting storage of fear memory
(Cold Spring Harbor Lab Press, 2013-02)
Late post-training activation of the ventral tegmental area (VTA)–hippocampus dopaminergic loop controls the entry of information into long-term memory (LTM). Nicotinic acetylcholine receptors (nAChR) modulate VTA function, ...
Neuropsychiatric symptoms related to cholinergic deficits in Parkinson’s disease
(Springer Nature, 2017)
Abstract: Given its ability to explain the most frequent motor symptoms of Parkinson’s disease (PD), degeneration of dopaminergic neurons has been considered one of the disease´s main pathophysiological features. Several ...
Rapid eye movement sleep deprivation induces an increase in acetylcholinesterase activity in discrete rat brain regions
(Associação Brasileira de Divulgação Científica, 2001-01-01)
Some upper brainstem cholinergic neurons (pedunculopontine and laterodorsal tegmental nuclei) are involved in the generation of rapid eye movement (REM) sleep and project rostrally to the thalamus and caudally to the medulla ...
Melanin-concentrating hormone projections to areas involved in somatomotor responses
(ELSEVIER SCIENCE BV, 2008)
The lateral hypothalamic area (LHA) participates in the integration of sensory information and somatomotor responses associated with hunger and thirst. Although the LHA is neurochemically heterogeneous, a particularly high ...
Antinociceptive effect of stimulating the zona incerta with glutamate in rats
(PERGAMON-ELSEVIER SCIENCE LTDOXFORD, 2012-05)
The zona incerta (ZI) is a subthalamic nucleus connected to several structures, some of them known to be involved with antinociception. The 21 itself may be involved with both antinociception and nociception. The antinociceptive ...
Segregated anatomical input to sub-regions of the rodent superior colliculus associated with approach and defense
(FRONTIERS RES FOUNDLAUSANNE, 2012)
The superior colliculus (SC) is responsible for sensorimotor transformations required to direct gaze toward or a way from unexpected, biologically salient events. Significant changes in the external world are signaled to ...
Coherence and frequency in the reticular activating system (RAS)
(Elsevier, 2012-10)
This review considers recent evidence showing that cells in the reticular activating system (RAS) exhibit 1) electrical coupling mainly in GABAergic cells, and 2) gamma band activity in virtually all of the cells. Specifically, ...
Pharmacotherapies for Parkinson’s disease symptoms related to cholinergic degeneration
(Informa Healthcare, 2016-10)
Introduction: Dopamine depletion is one of the most important features of Parkinson’s Disease (PD). However, insufficient response to dopaminergic replacement therapy suggests the involvement of other neurotransmitter ...
KCNQ4 in the reticular activating system (RAS): contribution to the circadian rhythm modulation
(Sociedad Argentina de Investigación en Neurociencia, 2020)
The M-current is a voltage-gated potassium current generated by channels composed by KCNQ2-5 subunits. The pedunculopontine nucleus (PPN) is part of the Reticular Activating System (RAS), associated with sleep regulation. ...