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Activation of platelet tissue factor is mediated by GPIba signailing with final activation of AKT
(2016)
Human platelets express tissue factor mRNA, synthesize the protein and store functionally silent
tissue factor (TF) which has procoagulant activity (PCA) after platelet activation. Platelet GPIbα plays
a major role in ...
Interaction of Human Platelets with Enterohemorrhagic E.coli O111, Induces an Increase in the Procoagulant Activity,Thrombin Generation and Adhesion to Endothelial Cells
(2014)
Acute inflammation in response to severe bacterial infection, results in
hemostatic abnormalities ranging from subclinical to sustained systemic
clotting activation leading to massive thrombin and fibrin formation ...
Platelets as mediators of Thromboinflammation in chronic Myeloproliferative Neoplasms
(Frontiers Research Foundation, 2019-06-14)
Chronic myeloproliferative neoplasms (MPN) are stem cell disorders driven by mutations in JAK2, CALR, or MPL genes and characterized by myeloid proliferation and increased blood cell counts. They encompass three closely ...
Isolation and characterization of four medium-size disintegrins from the venoms of Central American viperid snakes of the genera Atropoides, Bothrops, Cerrophidion and Crotalus
(2014-12)
Four disintegrins were isolated from the venoms of the Central American viperid snakes Atropoides mexicanus (atropoimin), Bothrops asper (bothrasperin), Cerrophidion sasai (sasaimin), and Crotalus simus (simusmin). ...
Isolation and characterization of four medium-size disintegrins from the venoms of Central American viperid snakes of the genera Atropoides, Bothrops, Cerrophidion and Crotalus
(2014-12)
Four disintegrins were isolated from the venoms of the Central American viperid snakes Atropoides mexicanus (atropoimin), Bothrops asper (bothrasperin), Cerrophidion sasai (sasaimin), and Crotalus simus (simusmin). ...