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Inhibition of tumor necrosis factor alpha secretion and prevention of liver injury in ethanol-fed rats by antisense oligonucleotides
(PERGAMON-ELSEVIER SCIENCE LTD, 2005-02-15)
Elevated serum tumor necrosis factor alpha JNF-alpha) levels predict mortality in patients with alcoholic liver disease. Administration of anti-TNF-alpha antibodies, obliteration of Kupffer cells or gut sterilization protect ...
Prevention of renal ischemic reperfusion injury using FTY 720 and ICAM-1 antisense oligonucleotides
(ELSEVIER SCIENCE INC, 2003)
Background. Renal damage secondary to ischemia-reperfusion injuries (I-R) is frequent in organ transplantation and adversely affects the graft survival. An important component of this damage is caused by initial adhesion ...
DMT1, a physiologically relevant apical Cu1+ transporter of intestinal cells
(2003)
Despite important advances in the under-standing of copper secretion and excretion, the molecular components of intestinal copper absorption remain a mys-tery. DMT1, also known as Nramp2 and DCT1, is the trans-porter ...
Distrofia Miotónica tipo 1: Fisiopatología y Avances en la Terapia Génica
(2014-12)
La distrofa miotónica tipo 1 (la
enfermedad muscular hereditaria mas
común en el adulto joven) es causada por
una expansión de la tripleta citosina-timinaguanina (CTG), la cual es inestable en las
líneas germinal y ...
Distrofia Miotónica tipo 1: Fisiopatología y Avances en la Terapia Génica
(2014-12)
La distrofa miotónica tipo 1 (la
enfermedad muscular hereditaria mas
común en el adulto joven) es causada por
una expansión de la tripleta citosina-timinaguanina (CTG), la cual es inestable en las
líneas germinal y ...
Targeting antisense mitochondrial ncRNAs inhibits murine melanoma tumor growth and metastasis through reduction in survival and invasion factors
(IMPACT JOURNALS LLC, 2016)
We reported that knockdown of the antisense noncoding mitochondrial RNAs (ASncmtRNAs) induces apoptotic death of several human tumor cell lines, but not normal cells, suggesting this approach for selective therapy against ...
Inhibition of UCP2 expression reverses diet-induced diabetes mellitus by effects on both insulin secretion and action
(Federation Amer Soc Exp BiolBethesdaEUA, 2007)