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Avaliação da atividade antitumoral in vitro e in vivo de novos complexos de rutênio contendo ácido salicílico e derivados
(Universidade Federal de São CarlosUFSCarPrograma Interinstitucional de Pós-Graduação em Ciências Fisiológicas - PIPGCFCâmpus São Carlos, 2021-04-30)
Cancer is a term used for diseases in which abnormal cells divide uncontrolled, spread, and invade other tissues through the blood and lymphatic systems. Breast cancer is one of the most common and with higher mortality ...
Depression promotes prostate cancer invasion and metastasis via a sympathetic-cAMP-FAK signaling pathway
(Springer Nature, 2018)
Abstract: Depression drives cancer progression and induces poor clinical outcome. However, the mechanisms
underlying depression and cancer outcomes are unclear. In this work, we investigated 98 prostate
cancer patients ...
The Fatty Acid Synthase Inhibitor Orlistat Reduces The Growth And Metastasis Of Orthotopic Tongue Oral Squamous Cell Carcinomas
(American Association for Cancer Research Inc., 2014)
Stable SET knockdown in head and neck squamous cell carcinoma promotes cell invasion and the mesenchymal-like phenotype in vitro, as well as necrosis, cisplatin sensitivity and lymph node metastasis in xenograft tumor models
(2014-02-20)
Abstract
Background
SET/I2PP2A is a multifunctional protein that is up-regulated in head and neck squamous cell carcinoma (HNSCC). The action of SET in HNSCC tumorigenicity ...
Stable SET knockdown in head and neck squamous cell carcinoma promotes cell invasion and the mesenchymal-like phenotype in vitro, as well as necrosis, cisplatin sensitivity and lymph node metastasis in xenograft tumor models
(BMC, 2014-02-20)
Background
SET/I2PP2A is a multifunctional protein that is up-regulated in head and neck squamous cell carcinoma (HNSCC). The action of SET in HNSCC tumorigenicity is unknown.
...
Avaliação do vetor retroviral bicistrônico Codificador de endostatina e interleucina-2 Para utilização em terapia gênica anti-tumoral
(Universidade Federal de São Paulo (UNIFESP), 2010-07-28)
Gene therapy has been used in preclinical studies and clinical trials in order to assuage or cure a disease. Retroviral vectors are tools for gene transfer are widely used. Bicistronic vectors are attractive alternatives ...
Commentary: Arginine vasopressin receptor 1a is a therapeutic target for castration-resistant prostate cancer
(Frontiers Media, 2020-01-10)
Prostate cancer patients managed with androgen-deprivation therapy usually recur after a few years and the disease gradually becomes castration-resistant prostate cancer (CRPC). The role of tumor cell plasticity, including ...