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Novel SARS-CoV-2 outbreak and COVID19 disease; a systemic review on the global pandemic
Since the beginning of the 21st century, several viral outbreaks have threatened
humankind and posed a new challenge to the modern healthcare system. The recent outbreak
in Wuhan (December 2019), China, represents a beta ...
Novel snakebite therapeutics must be tested in appropriate rescue models to robustly assess their preclinical efficacy
(2020)
In the field of antivenom research, development, and manufacture, it is often advised to follow the World Health Organization’s (WHO) guidelines for the production, control, and regulation of snake antivenom immunoglobulins, ...
Bile Acids and Nonalcoholic Fatty Liver Disease: Molecular Insights and Therapeutic Perspectives
(2017)
Nonalcoholic fatty liver disease (NAFLD) is a burgeoning health problem worldwide and an important risk factor for both hepatic and cardiometabolic mortality. The rapidly increasing prevalence of this disease and of its ...
ERp57 as a novel cellular factor controlling Prion biosynthesis: Therapeutic potential of protein disulfide isomerases
(2016)
Disturbance of endoplasmic reticulum (ER) proteostasis is observed in Prion-related disorders (PrDs). The protein disulfide isomerase ERp57 is a stress-responsive ER chaperone up-regulated in the brain of Creutzfeldt-Jakob ...