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Mostrando ítems 31-40 de 160
Estudo do papel do estrógeno na modulaçao da autofagia em um modelo de neurodegeneração pela superexpressão da proteína tau em zebrafish
(Universidade Federal de São Paulo, 2022-02-17)
Atualmente sabe-se que a formação dos emaranhados neurofibrilares, constituídos principalmente pela proteína tau hiperfosforilada, contribui para a patogenia da Doença de Alzheimer, que é caracterizada clinicamente pela ...
Doença de Alzheimer e sua relação com o alelo ε4 do gene da apolipoproteína E
(Universidade Federal de UberlândiaBrasilCiências Biológicas, 2022)
Cholinesterase inhibitors for Alzheimer's disease: Multitargeting strategy based on anti-Alzheimer's drugs repositioning
(Bentham Science Publishers, 2019)
Relationship Between Obesity, Alzheimer’s Disease, and Parkinson’s Disease: an Astrocentric View
(Humana Press Inc., 2017)
Hepcidin attenuates amyloid beta-induced inflammatory and pro-oxidant responses in astrocytes and microglia
(2017)
Alzheimer's disease (AD) is characterized by extracellular senile plaques, intracellular neurofibrillary tangles, and neuronal death. Aggregated amyloid-β (Aβ) induces inflammation and oxidative stress, which have pivotal ...
Tau Platelets correlates with regional brain atrophy in patients with Alzheimer’s disease
(2017)
BACKGROUND: Intracellular neurofibrillary tangles are part of the core pathology of Alzheimer's disease (AD), which are mainly composed of hyperphosphorylated tau protein. OBJECTIVES: The purpose of this study is to determine ...