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A structure-activity relationship study of quinone compounds with trypanocidal activity
(Elsevier B.V., 2014)
Core electron binding energy (CEBE) as descriptors in quantitative structure-activity relationship (QSAR) analysis of cytotoxicities of a series of simple phenols
(Wiley-v C H Verlag GmbhWeinheimAlemanha, 2007)
Molecular mechanisms in perirhinal cortex selectively necessary for discrimination of overlapping memories, but independent of memory persistence
(Society for Neuroscience, 2017-09)
Successful memory involves not only remembering over time but also keeping memories distinct. The ability to separate similar experiences into distinct memories is a main feature of episodic memory. Discrimination of ...
Prioritizing promising compounds in virtual screening campaigns
(Universidade Federal de Minas GeraisBrasilICB - DEPARTAMENTO DE BIOQUÍMICA E IMUNOLOGIAPrograma de Pós-Graduação em BioinformaticaUFMG, 2019-11-07)
A triagem virtual baseada na estrutura (SBVS) contribui significativamente para as etapas iniciais da descoberta de fármacos. No entanto, o SBVS geralmente depende de um processo bastante trabalhoso que consiste na seleção ...
Coordinated Role of Toll-Like Receptor-3 and Retinoic Acid-Inducible Gene-I in the Innate Response of Bovine Endometrial Cells to Virus
(Frontiers Media Sa, 2017-08-23)
Bovine herpesvirus-4 (BoHV-4) and bovine viral diarrhea virus (BVDV) infect the uterus of cattle, often resulting in reduced fertility, or abortion of the fetus, respectively. Here, exposure of primary bovine endometrial ...
Discriminating active from latent tuberculosis in patients presenting to community clinics
(Public Library of Science, 2012)
Background: Because of the high global prevalence of latent TB infection (LTBI), a key challenge in endemic settings is distinguishing patients with active TB from patients with overlapping clinical symptoms without active ...
Authentication and Discrimination of Whiskies of High Commercial Value by Pattern Recognition
(Springer, 2014-08)
An analytical method for a rapid and non-destructive classification and authentication of whiskies of high commercial value based on trademark and years of aging is presented. Molecular absorption spectroscopy was performed ...
Fibrillar organization in tendons: a pattern revealed by percolation characteristics of the respective geometric network
(International Academy of Ecology and Environmental Sciences, 2014)
Since the tendon is composed by collagen fibrils of various sizes connected between them through molecular cross-links, it sounds logical to model it via a heterogeneous network of fibrils. Using cross sectional images, ...
Coupling pathogen recognition to innate immunity through glycan-dependent mechanisms
(Elsevier Science, 2011-10)
Innate immune cells have evolved to sense microbial pathogens through pattern recognition receptors (PRRs), which interact with conserved pathogen-associated molecular patterns (PAMPs) to convey microbial information into ...