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Diverging biological roles among human monocyte subsets in the context of tuberculosis infection
(Portland Press, 2015-04)
Circulating monocytes (Mo) play an essential role in the host immune response to chronic infections. We previously demonstrated that CD16pos Mo were expanded in TB (tuberculosis) patients, correlated with disease severity ...
The role of neutrophils in Brucellosis
(American Society for Microbiology, 2020-10-14)
Brucellosis is a bacterial disease of domestic animals and humans. The pathogenic ability of Brucella organisms relies on their stealthy strategy and their capacity to replicate within host cells and to induce long-lasting ...
Cytokine and nitric oxide production by mouse macrophages infected with brazilian flaviviruses
(Instituto de Medicina Tropical, 2009)
The Flaviviridae family, Flavivirus genus includes viruses that are transmitted to vertebrates by infected mosquitoes or ticks. The genus Flavivirus includes a variety of viruses that cause diseases such as acute febrile ...
New insights into the immunobiology of mononuclear phagocytic cells and their relevance to the pathogenesis of cardiovascular diseases
(Frontiers Media S.A., 2018-01)
Macrophages are the primary immune cells that reside within the myocardium, suggesting that these mononuclear phagocytes are essential in the orchestration of cardiac immunity and homeostasis. Independent of the nature of ...
Estudio de nuevos inhibidores de la transcriptasa inversa no nucleosídicos con adictividad antiviral contra el virus de la inmunodeficiencia humana 1 en combinación con acetato de zinc, para su potencial uso como microbicidas de amplio espectro
(2013)
Los microbicidas constituyen una nueva herramienta, todavía en proceso de investigación, que podría ayudar en la prevención de la infección por los virus de la inmunodeficiencia humana (VIH) y otras infecciones de transmisión ...
Avaliação in vitro da ação de enzimas oriundas das NETs na replicação viral do hRSV
(Universidade Estadual Paulista (Unesp), 2021-03-05)
As infecções do trato respiratório são extremamente comuns sendo, o Vírus Sincicial Respiratório Humano (hRSV) o principal agente etiológico das infecções virais agudas do trato respiratório inferior, resultando mundialmente ...
Efeito regulador da PGE2 na produção de TNF-α e IL-17 na atividade microbicida na leishmaniose canina.
(Universidade Estadual Paulista (Unesp), 2019-08-15)
A leishmaniose canina (CanL) é causada pelo parasito intracelular Leishmania infantum. Devido ao alto parasitismo na pele o cão é considerado o principal reservatório urbano da L. Infantum. A prostaglandina-E2 (PGE2) possui ...
Extracción de polifenoles de plantas silvestres de zarzamora (Rubus spp.) para aplicaciones antimicrobianas
(Universidad Michoacana de San Nicolás de Hidalgo, 2014-08)
The Rubus genus presents plants as the blackberry and raspberry that develop in several States of the Mexican Republic, between which Michoacán's condition stands out, where there have been described species considered as ...
Análisis de la expresión de citocinas de la línea celular U937 incubada con NETs
(16/05/2012)
ABSTRACT: Neutrophils utilize phagocytosis and degranulation to efficiently kill microorganisms. A new microbicidal mechanism was described by Brinkmann and cols in which neutrophils die after releasing „Neutrophil ...