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Bioenergetics, mitochondrial dysfunction, and oxidative stress in the pathophysiology of septic encephalopathy
(Lippincott, Williams & Wilkins, 2018)
Temporal evolution of cardiac mitochondrial dysfunction in a type 1 diabetes model. Mitochondrial complex I impairment, and H2O2 and NO productions as early subcellular events
(Elsevier Science Inc, 2020-11)
The aim of this work was to study the early events that occur in heart mitochondria and to analyse the temporal evolution of cardiac mitochondrial dysfunction in a type 1 diabetes model. Male Wistar rats were injected with ...
Cell death induced by mitochondrial complex I inhibition is mediated by Iron Regulatory Protein 1
(Elsevier B.V., 2017)
© 2017 Elsevier B.V. Mitochondrial dysfunction and oxidative damage, often accompanied by elevated intracellular iron levels, are pathophysiological features in a number of neurodegenerative processes. The question arises ...
Rosiglitazone treatment prevents mitochondrial dysfunction in mutant huntingtinexpressing cells: possible role of peroxisome proliferator-activated receptor-gamma (PPARgamma) in the pathogenesis of Huntington disease.
(2008)
Peroxisome proliferator-activated receptor-gamma (PPARgamma) is a member of the PPAR family of transcription factors. Synthetic PPARgamma agonists are used as oral anti-hyperglycemic drugs for the treatment of non-insuli ...
Differential protective effects of quercetin, resveratrol, rutin and epigallocatechin gallate against mitochondrial dysfunction induced by indomethacin in Caco-2 cells
(Elsevier, 2012)
The beneficial effects of dietary polyphenols on health are due not only to their antioxidant properties but
also to their antibacterial, anti-inflammatory and/or anti-tumoral activities. It has recently been proposed
that ...
Mitochondrial alterations and apoptosis in smooth muscle from aged rats
(Elsevier B.V., 2014)
Hypertension linked to allostatic load: From psychosocial stress to inflammation and mitochondrial dysfunction
(Taylor & Francis Ltd, 2019-03)
Although a large number of available treatments and strategies, the prevalence of cardiovascular diseases continues to grow worldwide.émergingévidence supports the notion of counteracting stress as a critical component of ...
Mitochondria, myocardial remodeling, and cardiovascular disease
(2012)
The process of muscle remodeling lies at the core of most cardiovascular diseases. Cardiac adaptation to pressure or volume overload is associated with a complex molecular change in cardiomyocytes which leads to anatomic ...
Suppression of high-fat diet-induced obesity-associated liver mitochondrial dysfunction by docosahexaenoic acid and hydroxytyrosol co-administration
(Elsevier, 2020)
Objective: Obesity-induced by high-fat diet (HFD) is associated with liver steatosis, oxidative stress and mitochondrial dysfunction, which can be eluded by the co-administration of the lipid metabolism modulator docosahexaenoic ...