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Integrative transcriptome analysis identifies deregulated microRNA-transcription factor networks in lung adenocarcinoma
(2016-05-17)
Herein, we aimed at identifying global transcriptome microRNA (miRNA) changes and miRNA target genes in lung adenocarcinoma. Samples were selected as training (N = 24) and independent validation (N = 34) sets. Tissues were ...
GH Overexpression Alters Spermatic Cells MicroRNAome Profile in Transgenic Zebrafish
(2021-09-08)
Overexpression of growth hormone (GH) in gh-transgenic zebrafish of a highly studied lineage F0104 has earlier been reported to cause increased muscle growth. In addition to this, GH affects a broad range of cellular ...
Análise da expressão de miR-21-5p e miR-105-5p no soro de pacientes com câncer gástrico
(Universidade Federal de São Paulo, 2022-09-12)
O câncer gástrico (CG) é uma das mais frequentes e letais neoplasias do mundo.
Contudo, ainda existem poucas ferramentas eficazes para seu diagnóstico,
monitoramento e resposta ao tratamento. Estudos sobre biomarcadores ...
Monitoring of soluble pectin content in orange juice by means of MIR and TD-NMR spectroscopy combined with machine learning
(2020-12-01)
This study represents a rapid and non-destructive approach based on mid-infrared (MIR) spectroscopy, time domain nuclear magnetic resonance (TD-NMR), and machine learning classification models (ML) for monitoring soluble ...
Use of DSC in degree of conversion of dimethacrylate polymers: easier and faster than MIR technique
(2018-05-01)
This work aims to determine the degree of conversion of polymers obtained using diurethane dimethacrylate (UDMA) monomer by two different techniques: differential scanning calorimetry (DSC) and Fourier transform infrared ...
Efecto de metformina sobre los niveles miR-145 y miR-23b en células de cáncer de ovario epitelial
(Universidad de Chile, 2023)
El cáncer ovárico epitelial (COE) posee la tasa de mortalidad más alta entre los cánceres ginecológicos en el mundo, siendo en Chile la segunda causa de muerte por neoplasias ginecológicas. El COE se caracteriza por una ...
Expression of AIF, PARP, and miRNAs MIR-145, MIR-210, and MIR-486 Associated with Apoptosis in the Corpus Cavernosum of Rats Subjected to Chronic Alcoholism Model
(Soc Chilena Anatomia, 2020-12-01)
Previous studies from our group described the consequences of using ethanol on penile erection. Nevertheless, the molecular mechanisms surrounding microRNAs, apoptosis process and their relationship with erectile dysfunction ...
Expression of miR-155, miR-146a, and miR-326 in T1D patients from Chile: relationship with autoimmunity and inflammatory markers
(Sbem-Soc Brasil Endocrinología & Metabología, 2018)
Objective: The aim of this research was to analyze the expression profile of miR-155, miR-146a, and miR-326 in peripheral blood mononuclear cells (PBMC) of 47 patients with type 1 diabetes mellitus (T1D) and 39 control ...
Identification of a microRNA signature associated with progression of leukoplakia to oral carcinoma
(Oxford University Press, 2009-12-15)
MicroRNAs (miRs) are non-coding RNA molecules involved in cancer initiation and progression. Deregulated miR expression has been implicated in cancer; however, there are no studies implicating an miR signature associated ...