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Study of the in vitro metabolic profile of a new alpha(2)-adrenergic agonist Cheek for in rat and human liver microsomes by using liquid chromatography-multiple-stage mass spectrometry and nuclear magnetic resonance
(Elsevier B.V., 2019-08-05)
A potent synthetic alpha(2)-adrenergic agonist called PT-31, (3-(2-chloro-6-fluorobenzyI)-imidazolidine-2,4-dione), was recently detected as a potential drug to be used as an adjuvant drug to treat chronic pain. The excellent ...
Serum biochemical reference ranges for pregnant sheep
(2021-01-01)
Late pregnancy is accompanied by dramatic changes in the metabolism of sheep, in which the nutrient requirements increase and the metabolic capacity of ewes is under severe stress due to the rapid foetal growth and development ...
Metabolite fruit profile is altered in response to source–sink imbalance and can be used as an early predictor of fruit quality in nectarine
(Frontiers Media, 2021)
Peaches and nectarines [Prunus persica (L.) Batsch] are among the most exported
fresh fruit from Chile to the Northern Hemisphere. Fruit acceptance by final consumers
is defined by quality parameters such as the size, ...
Identification of Metabolite and Lipid Profiles in a Segregating Peach Population Associated with Mealiness in Prunus persica (L.) Batsch
(2020-04)
The peach is the third most important temperate fruit crop considering fruit production and harvested area in the world. Exporting peaches represents a challenge due to the long-distance nature of export markets. This ...
Metabolite‐based genome‐wide association study enables dissection of the flavonoid decoration pathway of wheat kernels
(Wiley Open AccessAssociation of Applied BiologistsSociety for Experimental BiologyBlackwell Publishing, 2020)
Application of in vitro Drug Metabolism Studies in Chemical Structure Optimization for the Treatment of Fibrodysplasia Ossificans Progressiva (FOP)
(Frontiers Media Sa, 2019-04-24)
Currently no approved treatment exists for fibrodysplasia ossificans progressiva (FOP) patients, and disease progression results in severe restriction of joint function and premature mortality. LDN-193189 has been demonstrated ...
Identification of Metabolite and Lipid Profiles in a Segregating Peach Population Associated with Mealiness in Prunus persica (L.) Batsch
(MDPI Multidisciplinary Digital Publishing Institute, 2020-04)
The peach is the third most important temperate fruit crop considering fruit production and harvested area in the world. Exporting peaches represents a challenge due to the long-distance nature of export markets. This ...
ABA and GA3 regulate the synthesis of primary and secondary metabolites related to alleviation from biotic and abiotic stresses in grapevine
(2017-03)
Plants are able to synthesize a large number of organic compounds. Among them, primary metabolites are known to participate in plant growth and development, whereas secondary metabolites are mostly involved in defense and ...