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In vitro cytotoxicity of some natural and semi-synthetic isocoumarins from Paepalanthus bromelioides
(2002-01-01)
Numerous natural compounds have a potential for therapeutic applications, but may have to be chemically modified to alter toxic side effects. We investigated structural parameters that could affect the cytotoxicity of ...
SYNTHESIS OF 2-(2-(HYDROXYMETHYL)PHENYL)ETHANOL DERIVATIVES AS POTENTIAL ANTIBACTERIAL AGENTS
(Sociedad Chilena de Química, 2009)
Synthesis, Antiproliferative Activities, And Computational Evaluation Of Novel Isocoumarin And 3,4-dihydroisocoumarin Derivatives
(Elsevier France-Editions Scientifiques Medicales ElsevierParis, 2016)
Biological evaluation and docking studies of natural isocoumarins as inhibitors for human kallikrein 5 and 7
(Elsevier B.V., 2011-10-15)
Human kallikrein 5 and 7 (KLK5 and KLK7) are trypsin-like and chymotrypsin-like serine proteases, respectively, and promising targets for the treatment of skin desquamation, inflammation and cancer. in an effort to develop ...
Two new compounds produced by Xylaria sp an endophytic fungus from Casearia sylvestris (Flacourtiaceae)
(Georg Thieme Verlag Kg, 2016-12-01)
Síntese de derivados 1,2,3-triazólicos de isocumarinas e 3,4-diidroisocumarinas com potencial atividade antimalárica in vitro
(Universidade Federal de Minas GeraisBrasilICX - DEPARTAMENTO DE QUÍMICAPrograma de Pós-Graduação em QuímicaUFMG, 2020-09-11)
This work reports the synthesis of a new class of 3,4-dihydroisocoumarins and 1,2,3-triazoles to obtain substances with biological activities. Thirty-one compounds were synthesized by an unprecedented hybridization of ...
AN ISOCOUMARIN DERIVATIVE FROM PAEPALANTHUS BROMELIOIDES
(Munksgaard Int Publ Ltd, 1994-08-15)
The structure of 5,7,9,10-tetramethoxy-3-methyl-1 H-naphtho[2,3-c]pyran-1-one, C18H18O6, a derivative of a natural isocoumarin isolated from Paepalanthus bromelioides, was determined by X-ray analysis, which unequivocally ...
Structure-antimicrobial activity of some natural isocoumarins and their analogues
(Urban & Fischer Verlag, 2005-05-01)
Three naturally occurring isocoumarins (paepalantine, paepalantine 9-O-beta-D-glucopyranoside and paepalantine 90-beta-D-allopyranosyl(1 -> 6) glucopyranoside) and two semi-synthetic analogues, 9,10-acylated compound and ...
Structure-antimicrobial activity of some natural isocoumarins and their analogues
(Urban & Fischer Verlag, 2005-05-01)
Three naturally occurring isocoumarins (paepalantine, paepalantine 9-O-beta-D-glucopyranoside and paepalantine 90-beta-D-allopyranosyl(1 -> 6) glucopyranoside) and two semi-synthetic analogues, 9,10-acylated compound and ...