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O potencial das células intestinais como fonte de células progenitoras pancreáticas
(Universidade Federal de Santa MariaBRMedicina VeterináriaUFSMPrograma de Pós-Graduação em Medicina Veterinária, 2012-02-24)
The objective of the present study was to establish a primary culture of intestinal cells
and to characterize the mRNA expression profile of genes related to pancreatic formation,
development and insulin metabolism. The ...
Mifepristone enhances insulin stimulated Akt phosphorylation and glucose uptake in skeletal muscle cells
(Elsevier, 2018)
Mifepristone is the only FDA-approved drug for glycaemia control in patients with Cushing's syndrome and type 2 diabetes. Mifepristone also has beneficial effects in animal models of diabetes and patients with antipsychotic ...
Fat Body p53 Regulates Systemic Insulin Signaling and Autophagy under Nutrient Stress via Drosophila Upd2 Repression
(Elsevier, 2020-10)
The tumor suppressor p53 regulates multiple metabolic pathways at the cellular level. However, its role in the context of a whole animal response to metabolic stress is poorly understood. Using Drosophila, we show that ...
Identification of insulin in the tear film and insulin receptor and IGF-I receptor on the human ocular surface
(Assoc Research Vision Ophthalmology IncBethesdaEUA, 2002)
Docohexaenoic acid improves the reduced umbilical vein relaxation observed in the offspring of pregnancies with maternal obesity
(2017)
Background and objectives: Maternal obesity (MO) is associated with increased risk of long term metabolic risk in the offspring (REF), probably involving mechanisms such as early programming of insulin resistance in fetal ...
Insulin therapy and fetoplacental vascular function in gestational diabetes mellitus
(2015)
What is the topic of this review? This review focuses on the effects of insulin therapy on fetoplacental vasculature in gestational diabetes mellitus and the potentiating effects of adenosine on this therapy. What advances ...