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Antioxidant and intestinal anti-inflammatory effects of plant-derived coumarin derivatives
(Elsevier B.V., 2014-02-15)
Background: Coumarins, also known as benzopyrones, are plant-derived products with several pharmacological properties, including antioxidant and anti-inflammatory activities. Based on the wide distribution of coumarin ...
Serine proteases in neutrophil extracellular traps exhibit anti-Respiratory Syncytial Virus activity
(2022-05-01)
Human respiratory syncytial virus (hRSV) is an infectious agent in infants and young children which there are no vaccines or drugs for treatment. Neutrophils are recruited for airway, where they are stimulated by hRSV to ...
Estudo do potencial terapêutico e profilático de N-Acetil-Cisteína na modulação da resposta imunológia na doença periodontal
(Universidade Federal de Minas GeraisBrasilICB - INSTITUTO DE CIÊNCIAS BIOLOGICASPrograma de Pós-Graduação em Biologia CelularUFMG, 2014-02-28)
Periodontal diseases have as a main component and inductor a bacterial dental
biofilm and are defined as an inflammation which affects the integrity of the dental
tissues. Recent studies estimate that 47.2 % of individuals ...
Influence of Parstatin on Experimental Periodontal Disease and Repair in Rats
(Amer Acad Periodontology, 2014-09-01)
Background: Parstatin is a 41-amino acid peptide, formed by proteolytic cleavage on activation of the protease activated receptor-1, with antiangiogenic properties. The purpose of this study is to evaluate the influence ...
Identificación inmunohistoquímica de neutrófilos en un modelo de inflamación en pez cebra (Danio rerio)
(Universidad de los AndesBiologíaFacultad de CienciasDepartamento de Ciencias Biológicas, 2019)
En los vertebrados una de las respuestas del sistema inmune es la inflamación, esta puede ser observada en modelos animales como el pez cebra, que en los últimos años ha adquirido importancia al poder realizar seguimiento ...
Chemical, enzymatic and cellular antioxidant activity studies of Agaricus blazei Murrill
(Academia Brasileira de Ciências, 2013-09-01)
Cogumelos apresentam propriedades nutricionais e medicinais bastante empregadas na manutenção da saúde humana e têm sido considerado por pesquisadores como possíveis fontes de seqÜestradores de radicais livres. Neste ...
Human mucosal leishmaniasis: Neutrophils infiltrate areas of tissue damage that express high levels of Th17-related cytokines
(WILEY-V C H VERLAG GMBH, 2010)
Mucosal leishmaniasis (ML) is characterised by severe tissue destruction. Herein, we evaluated the involvement of the IL-17-type response in the inflammatory infiltrate of biopsy specimens from 17 ML patients. IL-17 and ...
Characterization and quantifi cation of endogenous fatty acid nitroalkene metabolites in human urine
(American Society for Biochemistry and Molecular Biology, 2013-04)
The oxidation and nitration of unsaturated fatty acids transforms cell membrane and lipoprotein constituents into mediators that regulate signal transduction. The formation of 9-NO2-octadeca-9,11-dienoic acid and ...