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Heme oxygenase-1 is dispensable for the anti-inflammatory activity of intravenous immunoglobulin
(Nature Publishing Group, 2016-01)
Intravenous immunoglobulin G (IVIG) is used in the therapy of various autoimmune and inflammatory conditions. The mechanisms by which IVIG exerts anti-inflammatory effects are not completely understood. IVIG interacts with ...
Modulation of Antiviral Immunity by Heme Oxygenase-1
(2017)
Heme oxygenase-1 (H0-1) is a stress-inducible, anti-inflammatory, and cytoprotective enzyme expressed in most cell types in the organism. Under several stress stimuli, HO-1 expression and activity is up-regulated to catalyze ...
Nuclear translocation of haeme oxygenase-1 is associated to prostate cancer
(Nature Publishing Group, 2007)
The role of oxidative stress in prostate cancer has been increasingly recognised. Acute and chronic inflammations generate reactive oxygen species that result in damage to cellular structures. Haeme oxygenase-1 (HO-1) has ...
The effects of increased heme oxygenase-1 on the lymphoproliferative response in dogs with visceral leishmaniasis
(2017-05-01)
Canine visceral leishmaniasis (CVL) is known to affect the cellular immunity of infected dogs, through impairing lymphoproliferation and microbicidal mechanisms. This study examined heme oxygenase-1 (HO-1) and its metabolites, ...
Heme oxygenase 1 (HO-1) challenges the angiogenic switch in prostate cancer
(Springer, 2011-12)
Prostate cancer (PCa) is the second leading cause of cancer-associated death in men. Once a tumor is established it may attain further characteristics via mutations or hypoxia, which stimulate new blood vessels. Angiogenesis ...
Heme oxygenase up-regulation under salt stress protects nitrogen metabolism in nodules of soybean plants
(Pergamon-Elsevier Science Ltd, 2008-09)
The behaviour of enzymes involved in nitrogen metabolism, as well as oxidative stress generation and heme oxygenase gene and protein expression and activity, were analysed in soybean (Glycine max L.) nodules exposed to 50, ...
Pharmacological Induction of Heme Oxygenase-1 Impairs Nuclear Accumulation of Herpes Simplex Virus Capsids upon Infection
(2017)
Heme oxygenase-1 (HO-1) is an inducible enzyme that is expressed in response to physical and chemical stresses, such as ultraviolet radiation, hyperthermia, hypoxia, reactive oxygen species (ROS), as well as cytokines, ...
In vivo analysis of the presence of heme oxygenase-1, transcription factor Jun-D and CD90+/CD73+/CD105+/CD45- cells in the pulp of bleached teeth
(2019-01-01)
Aim: To investigate hydrogen peroxide (H2O2)-induced responsiveness in pulp cells using heme oxygenase-1 (HO-1) immunolabelling, Jun-D immunolabelling to study the effects of H2O2 on odontoblastic differentiation and ...