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Effects of in vitro exposure to butylparaben and di-(2 ethylhexyl) phthalate, alone or in combination, on ovarian function
(2016-09-01)
Parabens and phthalates are commercial chemicals widely used in the manufacture of industrial and consumer products frequently found as contaminants in biological fluids. We evaluated the effects of di-(2-ethylhexyl) ...
Expressão gênica do receptor do hormônio luteinizante (LHR), em células da teca e da granulosa de folículos antrais bovinos
(Universidade Estadual Paulista (Unesp), 2005)
Em células da teca e da granulosa, de folículos bovinos, foram detectados quatro transcritos alternativos do receptor do hormônio luteinizante (LHR). Apenas dois deles são traduzidos em proteínas funcionais com afinidades ...
Inhibin B and the ovarian follicular reserve
(2002-01-01)
Inhibins are dimeric glycoproteins composed of an α-subunit and a βA-subunit (inhibin A) or βB-subunit (inhibin B), which inhibits pituitary gonadotropin secretion of FSH. The inhibin B is a product of the cohort of antral ...
Inhibin B and the ovarian follicular reserve
(2002-01-01)
Inhibins are dimeric glycoproteins composed of an α-subunit and a βA-subunit (inhibin A) or βB-subunit (inhibin B), which inhibits pituitary gonadotropin secretion of FSH. The inhibin B is a product of the cohort of antral ...
Testosterona e gonadotrofina coriônica humana estimulam a esteroidogênese em células da granulosa de folículo pré-ovulatório de égua?Do testosterone and human chorionic gonadotropin stimulate steroidogenesis in granulosa cells of preovulatory follicle in mare?
(Universidade Federal de Minas Gerais, Escola de Veterinária, 2005)
Avaliou-se o papel da gonadotrofina coriônica humana (hCG) e da testosterona na produção de progesterona (P4) e 17beta -estradiol (E2) pelas células da granulosa cultivadas in vitro de folículo antral de égua. Os tratamentos ...
Effect of sialylation and complexity of FSH oligosaccharides on inhibin production by granulosa cells
(BioScientifica, 2013-01)
Granulosa cell inhibin A and B production is regulated by FSH and gonadal factors. This gonadotrophin is released as a mixture of glycoforms, which induce different biological responses in vivo and in vitro. Our aim was ...
Tumor necrosis factor-alpha activates nuclear factor-kappa B but does not regulate progesterone production in cultured human granulosa luteal cells
(PARTHENON PUBLISHING GROUP, 2007-07)
Background. The role of tumor necrosis factor-alpha (TNF-alpha) in granulosa luteal cell function and steroidogenesis is still controversial. Our aim was to examine the steroiclogenic response, together with the simultaneous ...
Molecular modelling predicts that 2-methoxyestradiol disrupts HIF function by binding to the PAS-B domain
(Elsevier Inc., 2019)
An estradiol metabolite, 2-methoxyestradiol (2ME), has emerged as an important regulator of ovarian physiology. 2ME is recognized as a potent anti-angiogenic agent in clinical trials and laboratory studies. However, little ...
Efecto de FSH sobre las células de la granulosa humanas cultivadas en condiciones hiperinsulínicas e hiperandrogénicas
(Universidad de Chile, 2017)
El Síndrome de Ovario Poliquístico (SOP), es una disfunción endocrino-ginecológica de alta prevalencia en mujeres en edad fértil (5 al 10%). Se estima que el 64% de estas pacientes pueden presentar hiperandrogenismo e ...