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Sensitizing Mucoepidermoid Carcinomas To Chemotherapy By Targeted Disruption Of Cancer Stem Cells
(Impact Journals LlcAlbany, 2016)
HDAC inhibition decreases XIST expression on female IVP bovine blastocysts
(2013-01-01)
During initial development, both X chromosomes are active in females, and one of them must be silenced at the appropriate time in order to dosage compensate their gene expression levels to male counterparts. Silencing ...
HDAC inhibition decreases XIST expression on female IVP bovine blastocysts
(2013-01-01)
During initial development, both X chromosomes are active in females, and one of them must be silenced at the appropriate time in order to dosage compensate their gene expression levels to male counterparts. Silencing ...
The effects of single-dose injections of modafinil and methamphetamine on epigenetic and functional markers in the mouse medial prefrontal cortex: potential role of dopamine receptors
(Pergamon-Elsevier Science Ltd, 2019-03)
METH use causes neuroadaptations that negatively impact the prefrontal cortex (PFC) leading to addiction and associated cognitive decline in animals and humans. In contrast, modafinil enhances cognition by increasing PFC ...
Repeated methamphetamine and modafinil induce differential cognitive effects and specific histone acetylation and DNA methylation profiles in the mouse medial prefrontal cortex
(Pergamon-Elsevier Science Ltd, 2018-03)
Methamphetamine (METH) and modafinil are psychostimulants with different long-term cognitive profiles: METH is addictive and leads to cognitive decline, whereas modafinil has little abuse liability and is a cognitive ...
Sequential establishment of marks on soluble histones H3 and H4
(2011-05-20)
Much progress has been made concerning histone function in the nucleus; however, following their synthesis, how their marking and subcellular trafficking are regulated remains to be explored. To gain an insight into these ...
A novel method for purification of polymerizable tubulin with a high content of the acetylated isotype
(Portland Press, 2013-02)
Tubulin can be acetylated/deacetylated on Lys40 of the α-subunit. Studies of the post-translational acetylation/deacetylation of tubulin using biochemical techniques require tubulin preparations that are enriched in AcTubulin ...
HDAC superfamily promoters acetylation is differentially regulated by modafinil and methamphetamine in the mouse medial prefrontal cortex
(Wiley Blackwell Publishing, Inc, 2019-02)
Dysregulation of histone deacetylases (HDAC) has been proposed as a potential contributor to aberrant transcriptional profiles that can lead to changes in cognitive functions. It is known that METH negatively impacts the ...