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PIB: A score to select sorafenib treatment candidates for hepatocellular carcinoma in resource-limited settings
(Baqiyatallah Research Center, 2018-10)
Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related death globally. Sorafenib, a multi-tyrosine kinase inhibitor, remains the standard of care for patients with inoperable or advanced-stage HCC. ...
Atividade antitumoral da secreção cutânea de Hypsiboas crepitans e de peptídeos derivados da pele dos anuros Hypsiboas crepitans e Leptodactylus labyrinthicus
(2017-02-13)
No presente trabalho foi avaliado pela primera vez o potencial anticâncer da secreção cutânea do anuro sul-americano Hypsiboas crepitans (Wied-Neuwied, 1824). O fracionamento por RP-HPLC de secreções de indivíduos coletados ...
Carcinoma hepatocelular como fator de risco para recorrência da infecção pelo vírus da hepatite B após o transplante de fígado: possível envolvimento das células neoplásicas na replicação viral
(Universidade Federal de Minas GeraisUFMG, 2007-07-03)
Background and aims: In the last years, ortothopic liver transplantation (OLT) has become an important modality of treatment for hepatitis B virus (HBV)-related liver disease patients. However, HBV infection may recur in ...
Treatment of Hepatocellular Carcinoma With Liver Transplantation: A Single-Center Experience From Brazil
(ELSEVIER SCIENCE INC, 2010)
Introduction. Orthotopic liver transplantation (OLT) is the treatment of choice of hepatocellular carcinoma (HCC) for patients with cirrhosis, mainly those with early HCC. Herein we have present the clinical characteristics ...
Lack of galectin-1 exacerbates chronic hepatitis, liver fibrosis, and carcinogenesis in murine hepatocellular carcinoma model
(Federation of American Societies for Experimental Biology, 2019-03)
Chronic liver inflammation (CLI) is a risk factor for development of hepatocellular carcinoma (HCC). Galectin-1 (Gal1) is involved in the regulation of inflammation, angiogenesis, and tumorigenesis, exhibiting multiple ...
Expressão de receptores de inositol 1,4,5-trifosfato do tipo 3 é um evento final comum ao desenvolvimento do carcinoma hepatocelular
(Universidade Federal de Minas GeraisBrasilICB - DEPARTAMENTO DE FISIOLOGIA E BIOFÍSICAPrograma de Pós-Graduação em Ciências Biológicas - Fisiologia e FarmacologiaUFMG, 2020-06-19)
Background: Hepatocellular carcinoma (HCC) is the second leading cause of cancer death worldwide. Several types of chronic liver disease predispose to HCC, and several different signaling pathways have been implicated in ...
Desempeño productivo de aves criollas mejoradas en fase de acabado alimentados con raciones incluidas con harina de cáscara de cacao
(Universidad Nacional Agraria de la SelvaPE, 2022)
El trabajo de investigación se realizó en la Unidad de aves de la Facultad de Zootecnia de la
Universidad Nacional Agraria de la Selva, con el objetivo de evaluar la respuesta productiva y
económica de pollos machos ...
HPA-1a/1b could be considered a molecular predictor of poor prognosis in chronic hepatitis C
(2019-01-01)
Introduction: HPA polymorphism has been associated with HCV presence and fibrosis progression in chronic hepatitis C. However, it is unknown if there is an association between HPA-1 polymorphism and hepatocellular carcinoma ...
PLAGL2-EGFR-HIF-1/2α Signaling Loop Promotes HCC Progression and Erlotinib Insensitivity
(John Wiley & Sons Inc., 2021-02)
Background and Aims: Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths worldwide, hence a major public health threat. Pleomorphic adenoma gene like-2 (PLAGL2) has been reported to play a ...
Arabidopsis thaliana Hcc1 is a Sco-like metallochaperone for Cu A assembly in Cytochrome c Oxidase
(Wiley Blackwell Publishing, Inc, 2019-07)
The assembly of the CuA site in Cytochrome c Oxidase (COX) is a critical step for aerobic respiration in COX-dependent organisms. Several gene products have been associated with the assembly of this copper site, the most ...