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Decyl Gallate as a Possible Inhibitor of N-Glycosylation Process in Paracoccidioides lutzii
(Amer Soc Microbiology, 2019-11-01)
The available antifungal therapeutic arsenal is limited. The search for alternative drugs with fewer side effects and new targets remains a major challenge. Decyl gallate (G14) is a derivative of gallic acid with a range ...
Improving bioreactor production of a recombinant glycoprotein in Escherichia coli: Effect of specific growth rate on protein glycosylation and specific productivity
(John Wiley & Sons Inc, 2019-02)
In the last decades bacterial glycoengineering emerged as a new field as the result of the ability to transfer the Campylobacter jejuni N- glycosylation machinery into Escherichia coli for the production of recombinant ...
A glycoproteomic approach reveals that the S-layer glycoprotein of Lactobacillus kefiri CIDCA 83111 is O- and N-glycosylated
(Elsevier Science, 2017-06)
In Gram-positive bacteria, such as lactic acid bacteria, general glycosylation systems have not been documented so far. The aim of this work was to characterize in detail the glycosylation of the S-layer protein of ...
Redesigning N-glycosylation sites in a GH3 β-xylosidase improves the enzymatic efficiency
(2019-11-14)
Background: β-Xylosidases are glycoside hydrolases (GHs) that cleave xylooligosaccharides and/or xylobiose into shorter oligosaccharides and xylose. Aspergillus nidulans is an established genetic model and good source of ...
Critical role of evolutionarily conserved glycosylation at Asn211in the intracellular trafficking and activity of sialyltransferase ST3Gal-II
(Portland Press, 2015-07)
ST3Gal-II, a type II transmembrane protein, is the main mammalian sialyltransferase responsible for GD1a and GT1b ganglioside biosynthesis in brain. It contains two putative N-glycosylation sites (Asn92 and Asn211). Whereas ...
Glycosylations in the globular head of the hemagglutinin protein modulate the virulence and antigenic properties of the h1n1 influenza viruses
(AMER ASSOC ADVANCEMENT SCIENCE, 2013)