Buscar
Mostrando ítems 31-40 de 163
Mild fasting hyperglycemia in children: high rate of glucokinase mutations and some risk of developing type 1 diabetes mellitus
(WILEY, 2009)
Background: Incidental hyperglycemia in children generates concern about the presence of preclinical type I diabetes mellitus (T1DM).
Crystal Structure, SAXS and Kinetic Mechanism of Hyperthermophilic ADP-Dependent Glucokinase from Thermococcus litoralis Reveal a Conserved Mechanism for Catalysis
(2013-06)
ADP-dependent glucokinases represent a unique family of kinases that belong to the ribokinase superfamily, being present
mainly in hyperthermophilic archaea. For these enzymes there is no agreement about the magnitude of ...
Three unreported glucokinase (GCK) missense mutations detected in the screening of thirty-two Brazilian kindreds for GCK and HNF1A-MODY
(Elsevier B.V., 2014-11-01)
Thirty-two Brazilian families with MODY phenotype were screened for GCK and HNF1A mutations. GCK mutations were found in 8 families, all patients with mild asymptomatic hyperglycaemia; 3 of them are novel: p.Asp365Asn, ...