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Distinct regions of loss of heterozygosity on 22q at different sites of head and neck squamous cell carcinomas
(2002-04-10)
Background: Frequent loss of heterozygosity (LOH) has been reported in many types of cancer, including head and neck carcinomas. Somatic deletions involving specific chromosomal regions are strongly associated with ...
Distinct regions of loss of heterozygosity on 22q at different sites of head and neck squamous cell carcinomas
(2002-04-10)
Background: Frequent loss of heterozygosity (LOH) has been reported in many types of cancer, including head and neck carcinomas. Somatic deletions involving specific chromosomal regions are strongly associated with ...
Deletion of Epstein-Barr virus latent membrane protein 1 gene in Japanese and Brazilian gastric carcinomas, metastatic lesions, and reactive lymphocytes
(1998-01-01)
A 30-bp deletion in the Epstein-Barr virus (EBV) latent membrane protein 1 (LMP1) gene has been reported in nasopharyngeal carcinoma and EBV- associated malignant lymphomas. Information on this deletion in EBV- associated ...
Autoimmune lymphoproliferative syndrome in a patient with a new minimal deletion in the death domain of the FAS gene
(W B SAUNDERS CO-ELSEVIER INC, 2008)
We present a case of autoimmune lymphoproliferative syndrome (ALPS) caused by a previously undescribed minimal deletion in the death domain of the FAS gene. ALPS is an uncommon disease associated with an impaired Fas-mediated ...
Estimating genomic instability mediated by Alu retroelements in breast cancer
(Sociedade Brasileira de Genética, 2009-01-01)
Alu-PCR is a relatively simple technique that can be used to investigate genomic instability in cancer. This technique allows identification of the loss, gain or amplification of gene sequences based on the analysis of ...