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Inibição do receptor do fator ativador de plaquetas promove redução de déficits neurológicos e neuroproteção na isquemia e reperfusão cerebral murina
(Universidade Federal de Minas GeraisUFMG, 2016-02-16)
Stroke is one of the most frequent causes of death and disability worldwide, and can cause a significant variety of clinical and socioeconomic burden. Different mechanisms are involved in the pathogenesis of stroke, for ...
Avaliação da angiogênese, inflamação e crescimento tumoral em camundongos com deleção gênica dos receptores para o PAF (PAFR-KO)
(Universidade Federal de Minas GeraisUFMG, 2006-02-08)
The endogenous lipid, platelet activating factor (PAF), is usually considered a pro-angiogenic mediator due to its exogenous in vitroand in vivo effects and to studies with PAF receptor (PAFR) antagonists in vivo. In this ...
Population attributable fraction of modifiable risk factors for dementia in Chile
(2022)
Introduction: Projected dementia incidence in Latin America and the Caribbean for the next decades is overwhelming. Access to local data, stratified by sex, is imperative for planning precise dementia-prevention ...
Platelet-activating factor receptor (PAF-R)-dependent pathways control tumour growth and tumour response to chemotherapy
(LONDON, 2010)
Abstract
Background
Phagocytosis of apoptotic cells by macrophages induces a suppressor phenotype. Previous data from our ...
Interaction of Macrophages with Apoptotic Cells Enhances HIV Type 1 Replication Through PGE2, PAF, and Vitronectin Receptor
(2006)
Phagocytosis of apoptotic cells by macrophages increases secretion of soluble mediators and generates an antiinflammatory environment. We previously reported that phagocytosis of apoptotic cells by HIV-1-infected macrophages ...
Renal microcirculation during Platelet-Activating Factor (PAF) antagonist (BN) administration
(Butterworth-heinemann, 1988-05-01)
Antiinflammatory and antiallodynic actions of the lignan niranthin isolated from Phyllanthus amarus - Evidence for interaction with platelet activating factor receptor
(Elsevier Science BvAmsterdamHolanda, 2006)