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A novel retrieval-dependent memory process revealed by the arrest of ERK1/2 activation in the basolateral amygdala
(Society for Neuroscience, 2018-03)
Fully consolidated fear memories can be maintained or inhibited by retrieval-dependent mechanisms depending on the degree of re-exposure to fear cues. Short exposures promote memory maintenance through reconsolidation, and ...
Disruptive effect of midazolam on fear memory reconsolidation: Decisive influence of reactivation time span and memory age
(Nature Publishing Group, 2009-01)
Benzodiazepine (BDZ) administered shortly after retrieval disrupts the reconsolidation of fear memory. In this research, we explored the way in which different factors that limit the emergence of such process may affect ...
Extinction cues do not reduce recovery of extinguished conditioned fear in humans
(Universidad de Almeria, 2018)
We evaluated whether an extinction cue can reduce (or prevent) the recovery of previously extinguished fear conditioning using an ABC renewal design in humans. Two experiments were carried out. In Experiment 1, two groups ...
Extinction cues do not reduce recovery of extinguished conditioned fear in humans
(2018)
We evaluated whether an extinction cue can reduce (or prevent) the recovery of previously extinguished fear conditioning using an ABC renewal design in humans. Two experiments were carried out. In Experiment 1, two groups ...
Spontaneous recovery from extinction in the infant rat
(Elsevier Science, 2014-11)
Within the Pavlovian conditioning framework, extinction is a procedure in which, after conditioning, the conditioned stimulus (CS) is repeatedly presented without the unconditioned stimulus (US). During this procedure the ...
Reconsolidation or Extinction: Transcription Factor Switch in the Determination of Memory Course after Retrieval
(Society for Neuroscience, 2011-04)
In fear conditioning, aversive stimuli are readily associated with contextual features. A brief reexposure to the training context causes fear memory reconsolidation, whereas a prolonged reexposure induces memory extinction. ...
LIMK, Cofilin 1 and actin dynamics involvement in fear memory processing
(Academic Press Inc Elsevier Science, 2020-07-11)
Long-term memory has been associated with morphological changes in the brain, which in turn tightly correlate with changes in synaptic efficacy. Such plasticity is proposed to rely on dendritic spines as a neuronal canvas ...
Effects of a flavonoid-rich fraction on the acquisition and extinction of fear memory: pharmacological and molecular approaches
(Universidade De Fortaleza, 2016)
The effects of flavonoids have been correlated with their ability to modulate the glutamatergic, serotoninergic, and GABAergic neurotransmission: the major targets of these substances are N-methyl-D-aspartic acid receptor ...
A sensory-enhanced context allows renewal of an extinguished fear response in the infant rat
(Elsevier Science, 2013-07)
Studies of extinction in preweanling rats have failed to find ABA-renewal in a fear conditioning paradigm. This result supports the hypothesis postulating ontogenetic qualitative differences in experimental extinction. A ...