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Epigenetic regulation of adult neural stem cells: implications for Alzheimer’s disease
(BMC, 2014)
Experimental evidence has demonstrated that several aspects of adult neural stem cells (NSCs), including their quiescence, proliferation, fate specification and differentiation, are regulated by epigenetic mechanisms. These ...
Epigenetic Pathways Regulating Bone Homeostasis: Potential Targeting for Intervention of Skeletal Disorders
(2014)
Epigenetic regulation utilizes different mechanisms to convey heritable traits to progeny cells that are independent of DNA sequence, including DNA silencing, post-translational modifications of histone proteins and the ...
BRDT is an essential epigenetic regulator for proper chromatin organization, silencing of sex chromosomes and crossover formation in male meiosis
(Public Library Science, 2018)
The double bromodomain and extra-terminal domain (BET) proteins are critical epigenetic
readers that bind to acetylated histones in chromatin and regulate transcriptional activity
and modulate changes in chromatin structure ...
SFPQ associates to LSD1 and regulates the migration of newborn pyramidal neurons in the developing cerebral cortex
(Elsevier, 2017)
The development of the cerebral cortex requires the coordination of multiple processes ranging from the proliferation of progenitors to the migration and establishment of connectivity of the newborn neurons. Epigenetic ...
SFPQ associates to LSD1 and regulates the migration of newborn pyramidal neurons in the developing cerebral cortex
(Elsevier, 2017)
The development of the cerebral cortex requires the coordination of multiple processes ranging from the proliferation of progenitors to the migration and establishment of connectivity of the newborn neurons. Epigenetic ...
SFPQ associates to LSD1 and regulates the migration of newborn pyramidal neurons in the developing cerebral cortex
(Elsevier, 2017)
The development of the cerebral cortex requires the coordination of multiple processes ranging from the proliferation of progenitors to the migration and establishment of connectivity of the newborn neurons. Epigenetic ...
Splicing regulation by long noncoding RNAs
(Oxford University Press, 2018-02)
Massive high-throughput sequencing techniques allowed the identification of thousands of noncoding RNAs (ncRNAs) and a plethora of different mRNA processing events occurring in higher organisms. Long ncRNAs can act directly ...