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Endophytic fungal compounds active against Cryptococcus neoformans and C. gattii.
(Nature Publishing Group, 2016)
A state-of-the-art review and prospective therapeutic applications of prenyl flavonoids as chemosensitizers against antifungal multidrug resistance in Candida albicans
(Bentham Science Publishers, 2022-02)
Multidrug resistance (MDR) in the opportunistic pathogen Candida albicans is defined as non-susceptibility to at least one agent in two or more drug classes. This phenomenon has been increasingly reported since the rise ...
Hybrid combinations containing natural products and antimicrobial drugs that interfere with bacterial and fungal biofilms
(Elsevier Gmbh, 2017-12)
Background: Biofilms contribute to the pathogenesis of many chronic and difficult-to eradicate infections whose treatment is complicated due to the intrinsic resistance to conventional antibiotics. As a consequence, there ...
The LUFS domain, its transcriptional regulator proteins, and drug resistance in the fungal pathogen Candida auris
The LUFS domain (LUG/LUH, Flo8, single-strand DNA-binding protein [SSBP]) is a well-conserved and apparently ancient region found in diverse proteins and taxa. This domain, which has as its most obvious structural feature ...
Candida species: Current epidemiology, pathogenicity, biofilm formation, natural antifungal products and new therapeutic options
(2013-01-01)
The incidence of fungal infections has increased significantly, so contributing to morbidity and mortality. This is caused by an increase in antimicrobial resistance and the restricted number of antifungal drugs, which ...
Nanotechnology-based Drug Delivery Systems for Dermatomycosis Treatment
(Bentham Science Publ Ltd, 2012-09-01)
Dermatomycosis are fungal infections that involve the stratum corneum of the skin and the nails, hair, and surfaces of mucous membranes. Mycological infections represent important public health disorders, and their incidence ...
Dermatófitos: interação patógeno-hospedeiro e resistência a antifúngicos
(Sociedade Brasileira de Dermatologia, 2010)
As micoses cutâneas estão entre as infecções mais comuns em humanos e se tornaram um importante problema de saúde pública, principalmente por causarem infecções invasivas em pacientes imunodeprimidos. Durante a infecção, ...
Antifungal Efficacy during Candida krusei Infection in Non-Conventional Models Correlates with the Yeast In Vitro Susceptibility Profile
(2013-03-28)
The incidence of opportunistic fungal infections has increased in recent decades due to the growing proportion of immunocompromised patients in our society. Candida krusei has been described as a causative agent of ...
Antifungal Efficacy during Candida krusei Infection in Non-Conventional Models Correlates with the Yeast In Vitro Susceptibility Profile
(2013-03-28)
The incidence of opportunistic fungal infections has increased in recent decades due to the growing proportion of immunocompromised patients in our society. Candida krusei has been described as a causative agent of ...