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Accidente por araña Loxosceles spp : reporte de caso y revisión de literatura
La picadura de la araña del género Loxosceles produce dermonecrosis en el sitio de la lesión y complicaciones sistémicas secundarias a reacciones enzimáticas de su veneno, lo que aumenta la tasa de mortalidad. El objetivo ...
Structural basis for metal ion coordination and the catalytic mechanism of sphingomyelinases D
(Amer Soc Biochemistry Molecular Biology Inc, 2005-04-08)
Sphingomyelinases D (SMases D) from Loxosceles spider venom are the principal toxins responsible for the manifestation of dermonecrosis, intravascular hemolysis, and acute renal failure, which can result in death. These ...
Tetracycline and penicillin resistant clostridium perfringens isolated from the fangs and venom glands of loxosceles laeta: its implications in loxoscelism treatment
(PERGAMON-ELSEVIER SCIENCE LTD, 2010)
The venom of Loxosceles spiders produces severe dermonecrotic damage, intravascular hemolysis, systemic alterations and risk of death. Clostridium perfringens is present in the microbial flora of the fangs and venom glands ...
Peçonha bruta de Loxosceles similis (Moenkhaus, 1898) ativa uma via apoptótica dependente de caspases em fibroblastos dérmicos humanos
(Universidade Federal de Minas GeraisUFMG, 2013-12-13)
Spiders from the Loxosceles genus represent a risk to human health due to the systemic and necrotic effect of their bite. The symptoms of envenomation with the brown spiders may vary from dermonecrosis in the majority of ...
Kinetic and mechanistic characterization of the Sphingomyelinases D from Loxosceles intermedia spider venom
(Elsevier B.V., 2006-03-15)
Envenomation by arachnids of the genus Loxosceles leads to local dermonecrosis and serious systemic toxicity mainly induced by sphingomyelinases D (SMase D). These enzymes catalyze the hydrolysis of sphingomyelin resulting ...
Structural basis for metal ion coordination and the catalytic mechanism of sphingomyelinases D
(Amer Soc Biochemistry Molecular Biology Inc, 2005-04-08)
Sphingomyelinases D (SMases D) from Loxosceles spider venom are the principal toxins responsible for the manifestation of dermonecrosis, intravascular hemolysis, and acute renal failure, which can result in death. These ...
Kinetic and mechanistic characterization of the Sphingomyelinases D from Loxosceles intermedia spider venom
(Elsevier B.V., 2006-03-15)
Envenomation by arachnids of the genus Loxosceles leads to local dermonecrosis and serious systemic toxicity mainly induced by sphingomyelinases D (SMase D). These enzymes catalyze the hydrolysis of sphingomyelin resulting ...
Brown spider (Loxosceles) venom toxins as potential biotools for the development of novel therapeutics
(2019-06-01)
Brown spider envenomation results in dermonecrosis with gravitational spreading characterized by a marked inflammatory reaction and with lower prevalence of systemic manifestations such as renal failure and hematological ...
Forty years of the description of brown spider venom phospholipases-D
(2020-01-01)
Spiders of the genus Loxosceles, popularly known as Brown spiders, are considered a serious public health issue, especially in regions of hot or temperate climates, such as parts of North and South America. Although the ...
The Anti-Inflammatory Effects of the Methanolic Extract and Fractions from Davilla elliptica St. Hil. (Dilleniaceae) on Bothrops jararaca Envenomation
(Mdpi Ag, 2015-06-01)
Inflammation and haemorrhage are the main characteristics of tissue injury in botropic envenomation. Although some studies have shown that anti-venom prevents systemic reactions, it is not efficient in preventing tissue ...