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In Vitro Apoptotic Cell Death Assessment
(2021-01-01)
Chemical compounds induce cytotoxicity by various mechanisms, including interference in membrane integrity, metabolism, cellular component degradation or release, and cell division. Between the classic death pathways, ...
Human peritoneal mesothelial cell death induced by high-glucose hypertonic solutioninvolves Ca2+ and Na+ Ions and oxidative stress with the participation of PKC/NOX2 andPI3K/Akt pathways
(Frontiers Media, 2017)
Chronic peritoneal dialysis (PD) therapy is equally efficient as hemodialysis while providing greater patient comfort and mobility. Therefore, PD is the treatment of choice for several types of renal patients. During PD, ...
Cardiomyocyte death: mechanisms and translational implicationsCELL DEATH & DISEASECELL DEATH DIS
(NATURE PUBLISHING GROUP, 2011)
Cardiomyocyte death: mechanisms and translational implicationsCELL DEATH AND DISEASECELL DEATH DIS
(NATURE PUBLISHING GROUP, 2011)
Cardiomyocyte death: mechanisms and translational implicationsCELL DEATH AND DISEASECELL DEATH DIS
(NATURE PUBLISHING GROUP, 2011)
Ceramide Induces the Death of Retina Photoreceptors Through Activation of Parthanatos
(Springer, 2019-07)
Ceramide (Cer) has a key role inducing cell death and has been proposed as a messenger in photoreceptor cell death in the retina. Here, we explored the pathways induced by C2-acetylsphingosine (C2-Cer), a cell-permeable ...
Sudden unexpected death in epilepsy: an important concern
(Faculdade de Medicina / USP, 2011-01-01)
Epilepsy is one of the most common neurologic problems worldwide. Unfortunately, individuals with epilepsy are at higher risk of death than the general population, and sudden unexpected death in epilepsy is the most important ...
New Insights into the Mechanism of Action of the Cyclopalladated Complex (CP2) in Leishmania: Calcium Dysregulation, Mitochondrial Dysfunction, and Cell Death
(American Society for Microbiology, 2022-01-18)
The current treatment of leishmaniasis is based on a few drugs that present several drawbacks, such as high toxicity, difficult administration route, and low efficacy. These disadvantages raise the necessity to develop ...
Diazoxide protects against methylmalonate-induced neuronal toxicity
(Academic Press Inc Elsevier ScienceSan DiegoEUA, 2006)