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Mostrando ítems 31-40 de 81
Creutzfeldt-Jakob disease and inclusion body myositis: Abundant disease-associated prion protein in muscle
(Wiley-Blackwell, 2004-01-01)
Pathological prion protein (PrPSc) is the hallmark of prion diseases affecting primarily the central nervous system. Using immunohistochemistry, paraffin-embedded tissue blot, and Western blot, we demonstrated abundant ...
Tumor frontal, trastorno afectivo y encefalopatía. Discusión del caso clínico presentado en el volumen 6, número 2
(Universidad del RosarioEscuela de Medicina y Ciencias de la Salud, 2010)
We report a case of a 65 years old female patient, who was admitted to the hospital with non specific neurological symptoms and who had preliminary imagenological findings of an extra-axial tumor mass (a meningioma of the ...
Tumor frontal, trastorno afectivo y encefalopatía. Discusión del caso clínico presentado en el volumen 6, número 2
(Universidad del RosarioEscuela de Medicina y Ciencias de la Salud, 2010)
We report a case of a 65 years old female patient, who was admitted to the hospital with non specific neurological symptoms and who had preliminary imagenological findings of an extra-axial tumor mass (a meningioma of the ...
Complex Interaction between Resident Microbiota and Misfolded Proteins: Role in Neuroinflammation and Neurodegeneration
(2020)
Neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD) and Creutzfeldt-Jakob disease (CJD) are brain conditions affecting millions of people worldwide. These diseases are associated with the ...
Biochemical and structural studies of the prion protein polymorphism
(2001)
A hallmark event in transmissible spongiform encephalopathies is the conversion of the physiological prion protein into the disease-associated isoform. A natural polymorphism at codon 129 of the human prion gene, resulting ...
Crossing the species barrier by PrPSc replication in vitro generates unique infectious Prions
(CELL PRESS, 2008-09-05)
Prions are unconventional infectious agents composed exclusively of misfolded prion protein (PrPSc), which transmits the disease by propagating its abnormal conformation to the cellular prion protein (PrPC). A key ...
Trophic factors in cerebrospinal fluid and spinal cord of patients with tropical spastic paraparesis, HIV, and Creutzfeldt-Jakob disease
(2006)
HTLV-1-associated myelopathy/tropical spastic paraparesis (TSP/HAM) is a chronic CNS disease characterized by axomyelinic degeneration of the long axons of corticospinal tracts. Levels of NGF, NT-3, NT-4/5, BDNF, GDNF, ...
Clinical findings in Creutzfeldt-Jakob disease mimicking dementia with Lewy bodies
(Academia Brasileira de Neurologia - ABNEURO, 2008-01-01)