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High Content Screening of a Kinase-Focused Library Reveals Compounds Broadly-Active against Dengue Viruses
(2013-02-01)
Dengue virus is a mosquito-borne flavivirus that has a large impact in global health. It is considered as one of the medically important arboviruses, and developing a preventive or therapeutic solution remains a top priority ...
Molecular Aspects of the Dengue Virus Infection Process: A Review
(Bentham Science Publ Ltd, 2018-01-01)
Background: At the present time, dengue is one of the most important arboviruses affecting man, becoming a serious global public health problem, especially in subtropical and tropical countries, where environmental conditions ...
Bronchiectasis is associated with human T-lymphotropic virus 1 infection in an Indigenous Australian population
(Oxford University Press, 2012)
Background. Recent studies suggest that infection with human T-lymphotropic virus 1 (HTLV-1) might be associated with bronchiectasis among Indigenous Australians. The present study compared the clinical characteristics and ...
Machine Learning and Bayes Probability For Detecting Camouflaged Mini Pandemic at the Waves of Covid-19
(IEEE, 2022)
This paper present a methodology based at Machine Learning and a theory backed by the Bayes probability to identify rare strains that might not be in coherence with the corona virus. By using the criteria of Tom Mitchell ...
Challenges and perspectives in the discovery of dengue virus entry inhibitors
(Bentham Science Publishers, 2021-05)
Dengue virus (DENV) disease has become one of the major challenges inpublic health. Currently, there is no antiviral treatment for this infection. Since humantransmission occurs via mosquitoes of the Aedes genus, most ...
Challenges and approaches in the discovery of human immunodeficiency virus type-1 non-nucleoside reverse transcriptase inhibitors
(John Wiley & Sons Inc, 2019-07)
The type I human immunodeficiency virus (HIV-1) pandemic affecting over 37 million people worldwide continues, with 1.8 million people newly infected each year. Highly active antiretroviral therapy is efficient at reducing ...
Prediction of the binding mode of N-2-phenylguanine derivative inhibitors to herpes simplex virus type 1 thymidine kinase
(Kluwer Academic PublDordrechtHolanda, 1998)
HIV-1 Nucleotide Sequence Comprehensive Analysis: A Computational Approach
(Bentham Science Publishers, 2018)