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Genotoxicity assessment of the antimalarial compound artesunate in somatic cells of mice
(Elsevier B.V., 2011-06-01)
Artesunate is a derivate of artemisinin that is both an antimalarial agent and acts cytotoxically on tumor cells. Despite its therapeutic use, its in vivo genotoxic potential has still not been evaluated. This study, ...
Lapachol Induces Clastogenic Effects in Rats
(Georg Thieme Verlag Kg, 2010-06-01)
Lapachol is a naturally occurring naphthoquinone derivative found in the heartwood of several plants, particularly those of the genus Tabebuia (Bignoneaceae). Despite its use as a therapeutic product with anti-inflammatory, ...
Lapachol Induces Clastogenic Effects in Rats
(Georg Thieme Verlag Kg, 2010-06-01)
Lapachol is a naturally occurring naphthoquinone derivative found in the heartwood of several plants, particularly those of the genus Tabebuia (Bignoneaceae). Despite its use as a therapeutic product with anti-inflammatory, ...
Genotoxic effects of (-)-cubebin in somatic cells of mice
(Wiley-Blackwell, 2014)
In vivo genotoxicity assessment of nerolidol
(Wiley-Blackwell, 2014)
Genotoxicity assessment of the antimalarial compound artesunate in somatic cells of mice
(Pergamon-Elsevier B.V. Ltd, 2014)
Lack of clastogenic/genotoxic effects of Baccharis dracunculifolia extract on Swiss mouse peripheral blood cells
(Funpec-editora, 2008-01-01)
Baccharis dracunculifolia de Candole (DC) ( Asteraceae) is indigenous throughout southeastern Latin America and is used by local people in traditional medicine. This plant is known to be the source of resin for the highly ...
Effects of the polysaccharide beta-glucan on clastogenicity and teratogenicity caused by acute exposure to cyclophosphamide in mice
(Academic Press Inc. Elsevier B.V., 2009-04-01)
Alterations that could lead to the cancer development may also be related to an adverse development of offspring in experimental animals. Some functional foods, which contain the polysaccharide beta-glucan, have been ...
Assessment of the potential clastogenic/aneugenic risk of Casearia sylvestris extract using in vivo assays
(2007-12-01)
Casearia sylvestris (Flacourtiaceae) is a plant which grows in wild and has been widely used in folk medicine. In this study, clastogenic/aneugenic properties of Casearia sylvestris crude ethanolic extract were evaluated ...
Lack of clastogenic/genotoxic effects of Baccharis dracunculifolia extract on Swiss mouse peripheral blood cells
(Funpec-editora, 2008-01-01)
Baccharis dracunculifolia de Candole (DC) ( Asteraceae) is indigenous throughout southeastern Latin America and is used by local people in traditional medicine. This plant is known to be the source of resin for the highly ...