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The panicolytic-like effect of fluoxetine in the elevated T-maze is mediated by serotonin-induced activation of endogenous opioids in the dorsal periaqueductal grey
(SAGE PUBLICATIONS LTDLONDON, 2012)
Serotonin (5-HT), opioids and the dorsal periaqueductal grey (DPAG) have been implicated in the pathophysiology of panic disorder. In order to study 5-HT-opioid interaction, the opioid antagonist naloxone was injected ...
O tratamento crônico com fluoxetina reverte os efeitos nociceptivo e antinociceptivo induzidos pela ativação dos receptores 5-HT1A e 5-HT2C da amídala de camundongos confinados aos braços do labirinto em cruz elevado
(Universidade Federal de São CarlosUFSCarPrograma Interinstitucional de Pós-Graduação em Ciências Fisiológicas - PIPGCFCâmpus São Carlos, 2019-05-31)
Several studies indicate that anxiety and depression may be accompanied by symptoms of severe pain with no precise location or apparent lesions. Several evidences demonstrate that some antidepressive drugs used in the ...
Beneficial effect of fluoxetine and dertraline on chronic stress-induced tumor crowth and cell dissemination in a mouse model of lymphoma : crucial role of antitumor immunity
(Frontiers, 2018)
Abstract: Clinical data and experimental studies have suggested a relationship between psychosocial factors and cancer prognosis. Both, stress effects on the immune system and on tumor biology were analyzed independently. ...
Síndrome do climatério
(2005-12-01)
The climateric is characterized by progressive hipoestrogenism and by tissue and functional alterations that leads the women to aging. The diagnosis approach needs to consider the symptoms originated by estrogenic deficiency ...
Ethopharmacological evaluation of the rat exposure test: A prey-predator interaction test
(2013-03-01)
The rat exposure test (RET) is a prey (mouse)-predator (rat) situation that activates brain defensive areas and elicits hormonal and defensive behavior in the mouse. Here, we investigated possible correlations between the ...
Ethopharmacological evaluation of the rat exposure test: A prey-predator interaction test
(2013-03-01)
The rat exposure test (RET) is a prey (mouse)-predator (rat) situation that activates brain defensive areas and elicits hormonal and defensive behavior in the mouse. Here, we investigated possible correlations between the ...
Chronic fluoxetine treatment induces structural plasticity and selective changes in glutamate receptor subunits in the rat cerebral cortex
(PERGAMON-ELSEVIER SCIENCE LTD, 2010-08-11)
It has been postulated that chronic administration of antidepressant drugs induces delayed structural and molecular adaptations at glutamatergic forebrain synapses that might underlie mood improvement. To gain further ...