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MABp1 for the treatment of colorectal cancer
(Taylor & Francis Online, 2017)
Inflammation is an established process in colorectal cancer development and a hallmark of progression, and pro-inflammatory cytokines have been implicated in the morbidity and functional compromise associated with malignancy. ...
MABp1 for the treatment of colorectal cancer
(Taylor & Francis Online, 2017)
Inflammation is an established process in colorectal cancer development and a hallmark of progression, and pro-inflammatory cytokines have been implicated in the morbidity and functional compromise associated with malignancy. ...
Competitive glucose metabolism as a target to boost bladder cancer immunotherapy
(Nature Publishing Group, 2020-01-17)
Bladder cancer - the tenth most frequent cancer worldwide - has a heterogeneous natural history and clinical behaviour. The predominant histological subtype, urothelial bladder carcinoma, is characterized by high recurrence ...
Escaping Antiangiogenic Therapy: Strategies Employed by Cancer Cells
(MDPI AG, 2016)
Tumor angiogenesis is widely recognized as one of the hallmarks of cancer. Consequently, during the last decades the development and testing of commercial angiogenic inhibitors has been a central focus for both basic and ...
Mitochondrial genome instability in colorectal adenoma and adenocarcinoma
(2015-11-01)
Mitochondrial dysfunction is regarded as a hallmark of cancer progression. In the current study, we evaluated mitochondrial genome instability and copy number in colorectal cancer using Next Generation Sequencing approach ...
Deregulation of energy metabolism as a cause and consequence of oncogenic process: review of literature
(2016)
The reprogramming of energy metabolism is an emerging hallmark of cancer that has not yet been demonstrated in all tumor models, and there are aspects which still not entirely clear. This review enrolled and analyzed data ...
Single cell "glucose nanosensor" verifies elevated glucose levels in individual cancer cells
(ACS Publications, 2019)
In vivo and in vitro models of hepatocellular carcinoma: Current strategies for translational modeling
(2021-11-01)
Hepatocellular carcinoma (HCC) is the sixth most common cancer worldwide and the third leading cause of cancer‐related death globally. HCC is a complex multistep disease and usually emerges in the setting of chronic liver ...
Identifying General Tumor and Specific Lung Cancer Biomarkers by Transcriptomic Analysis
(MDPI, 2022-07)
The bioinformatic pipeline previously developed in our research laboratory is used to identify potential general and specific deregulated tumor genes and transcription factors related to the establishment and progression ...
Endoplasmic Reticulum-Mitochondria Calcium Communication and the Regulation of Mitochondrial Metabolism in Cancer: A Novel Potential Target
(2017)
Cancer is characterized by an uncontrolled cell proliferation rate even under low nutrient availability, which is sustained by a metabolic reprograming now recognized as a hallmark of cancer. Warburg was the first to ...