Buscar
Mostrando ítems 31-40 de 2165
CYP2D6 polymorphism and its clinical implications
(Pharmacological and Toxicological Aspects 2010:1-20, 2010)
CY P2D6 is the most important enzyme in the metabolism ofdrugsandisresponsibleforthe metabolism of25% of all drugs currently available on the market. CYP 2D6 is not only expressed in liver but also in gut and brain neurons, ...
CYP2D6 polymorphism and its clinical implications
(Pharmacological and Toxicological Aspects, 2010, 2010)
Abstract. CYP2D6 is the most important enzyme in the
metabolism of drugs and is responsible for the metabolism of 25%
of all drugs currently available on the market. CYP2D6 is not only
expressed in liver but also in gut ...
Enantioselective inhibition of human CYP2C19 by the chiral pesticide ethofumesate: Prediction of pesticide-drug interactions in humans
(2021-08-25)
Ethofumesate is a chiral herbicide that may display enantioselective behavior in humans. For this reason, the enantioselective potential of ethofumesate and its main metabolite ethofumesate-2-hydroxy to cause pesticide-drug ...
CYPs molecular biomarkers in rainbow trout Oncorhynchus mykiss to assess oil contamination in a Patagonian stream.
(2017)
Cytochrome P450 (CYP) gene expressions were studied by semi-quantitative polymerase chain reaction (PCR) to assess oil pollution using liver and gills of juvenile rainbow trout Oncorhynchus mykiss sampled from La Mina ...
A de novo unequal cross-over mutation between CYP11B1 and CYP11B2 genes causes familial hyperaldosteronism type I
(2010)
Familial hyperaldosteronism type I (FH-I) is an autosomal dominant disorder caused by an unequal cross-over of the gene encoding steroid 11β-hydroxylase (CYP11B1) and aldosterone synthase (CYP11B2), giving rise to a chimeric ...
Widespread distribution of resistance to triazole fungicides in Brazilian populations of the wheat blast pathogen
(2021-02-01)
Fungicides have not been effective in controlling the wheat blast disease in Brazil. An earlier analysis of 179 isolates of Pyricularia oryzae Triticum lineage (PoTl) sampled from wheat fields across six populations in ...
A de novo unequal cross-over mutation between cyp11b1 and cyp11b2 genes causes familial hyperaldosteronism type i
(SPRINGER, 2011)
Familial hyperaldosteronism type I (FH-I) is an autosomal dominant disorder caused by an unequal cross-over of the gene encoding steroid 11 beta-hydroxylase (CYP11B1) and aldosterone synthase (CYP11B2), giving rise to a ...