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In Vitro Regulation of CCL3 and CXCL12 by Bacterial By-products Is Dependent on Site of Origin of Human Oral Fibroblasts
(Elsevier B.V., 2014-01-01)
Introduction: Production of chemokines by tissue resident cells is one of the main mechanisms involved in the inflammatory infiltrate formation during inflammation. The specific ability of fibroblasts from different oral ...
CXCL12a/CXCR4b acts to retain neutrophils in caudal hematopoietic tissue and to antagonize recruitment to an injury site in the zebrafish larva
(Springer Verlag, 2017)
© 2017, Springer-Verlag Berlin Heidelberg. Neutrophils are a major component of the innate immune response and the most abundant circulating cell type in humans and zebrafish. The CXCL12/CXCR4 ligand receptor pair plays a ...
CXCL12 rs1801157 polymorphism and expression in peripheral blood from breast cancer patients
(ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD, 2011)
The role of chemokines has been extensively analyzed both in cancer risk and tumor progression. Among different cytokines, CXCR4 and its ligand CXCL12 have been recently subjected to a closer examination. The single-nucleotide ...
Activation profile of CXCL8-stimulated neutrophils and aging
(ElsevierSan Diego, 2013-03)
Neutrophils are pivotal effector cells of innate immunity representing the first line of defense against aggression. They are the first cells to arrive at the site of the aggression, where they can directly eliminate the ...