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Avaliação clínica de Rattus norvegicus após terapia antiinflamatória com inibidor seletivo ou não para COX-2 por extrapolação alométrica
(Universidade Federal de Santa MariaBRMedicina VeterináriaUFSMPrograma de Pós-Graduação em Medicina Veterinária, 2004-08-02)
The anti-inflammatories no esteroidais (AINEs) they are the drugs of larger prescription all over the world, for humans and for animals. They combat the inflammation, the pain, the temperature increase, could also inhibit ...
Corticosteroids or Cyclooxygenase 2-Selective Inhibitor Medication for the Management of Pain and Swelling After Third-Molar Surgery
(Lippincott Williams & WilkinsPhiladelphiaEUA, 2011)
Análise in silico de um novo composto possível inibidor de ciclooxigenase 2 utilizando docking molecular
(Universidade Federal de São CarlosUFSCarCâmpus São CarlosBiotecnologia - Biotec-Ar, 2021-01-04)
This work describes the study of the formation of complexes between the enzyme cyclooxygenase (COX-2) and some of its inhibitors. For this purpose, the known inhibitors celecoxib (CEL), rofecoxib (RCX) and Korean 21 and ...
Protective effects of etoricoxib, a selective inhibitor of cyclooxygenase-2, in experimental periodontitis in rats
(2005-06-01)
Background: The purpose of the present study was to evaluate the effect of a potent selective cyclooxygenase-2 (COX-2) inhibitor, etoricoxib, on the prevention of alveolar bone loss in experimental periodontitis induced ...
Immunoexpression of cyclooxygenase-1 and -2 in ulcerative colitis
(Associação Brasileira de Divulgação Científica, 2007-07-01)
Ulcerative colitis (UC) is a disease of the colon and rectum characterized by a nonspecific chronic inflammation mediated by the concerted response of cellular and humoral events. Prostaglandins are synthesized by ...
Síntese e modelagem molecular do novo derivado indolinônico como candidato a antiinflamatório COX-2 seletivo
(2007-12-01)
Anti-inflammatory drugs are known to be the most widely-marketed drugs in the world, despite their serious side effects, mainly on the gastrointestinal tract. Thus, there are constant efforts to discover new prototypes ...
Síntese e modelagem molecular do novo derivado indolinônico como candidato a antiinflamatório COX-2 seletivo
(2007-12-01)
Anti-inflammatory drugs are known to be the most widely-marketed drugs in the world, despite their serious side effects, mainly on the gastrointestinal tract. Thus, there are constant efforts to discover new prototypes ...
Cox 1 and cox 2 inhibitions by a decoction of andean species from San Juan province, Argentine
(Sociedad de Biología de Cuyo, 2019)
Plants are a source of bioactive metabolites; the ability to act in multiple signalling pathways characteristic of inflammatory processes has been reported. The aim is to obtain alternative drugs with higher potency and ...