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Crystal structure, DNA binding studies, nucleolytic property and topoisomerase I inhibition of zinc complex with 1,10-phenanthroline and 3-methyl-picolinic acid
(Springer, 2010-02-01)
Crystal structure analysis of the zinc complex establishes it as a distorted octahedral complex, bis(3-methylpicolinato-kappa(2) N,O)(2)(1,10-phenanthroline-kappa(2) N,N)-zinc(II) pentahydrate, [Zn(3-Me-pic)(2)(phen)]center ...
The Bacteriophage lambdaDNA packaging enzyme: Identification of four structural domains of the gpNu1 subunit using limited proteolysis
(Sociedad de Biología de Chile, 2001)
In situ hybridization of bat chromosomes with human (TTAGGG)n probe, after previous digestion with Alu I
(Sociedade Brasileira de Genética, 2014)
Optimal number of spacers in CRISPR arrays
(2017)
Prokaryotic organisms survive under constant pressure of viruses. CRISPR-Cas system provides its prokaryotic host with an adaptive immune defense against viruses that have been previously encountered. It consists of two ...
Targeting the Transposase Domain of the DNA Repair Component Metnase to Enhance Chemotherapy
(AMER ASSOC CANCER RESEARCHPHILADELPHIA, 2012)
Previous studies have shown that the DNA repair component Metnase (SETMAR) mediates resistance to DNA damaging cancer chemotherapy. Metnase has a nuclease domain that shares homology with the Transposase family. We therefore ...
Estudo da interação e clivagem de DNA por complexos binucleares de Fe(III)-Zn(II) e mononucleares de Fe(III) contendo grupos poliaromáticos e cadeia lateral funcionalizada
(2020)
Este trabalho tem como objetivo investigar a interação e clivagem do DNA por 6 complexos binucleares de Fe(III)-Zn(II): C12, C12a, C12aet, C14, C14a e C14aet e dois complexos mononucleares de Fe(III): C12b e C14b, cujos ...
INVESTIGATIONS ON NUCLEASE ACTIVITY OF TRANS MIXED LIGAND- COPPER(II) COMPLEXES WITH ORTHO SUBSTITUTED AROMATIC OXIMES AND HETEROCYCLIC BASES
(Sociedad Chilena de Química, 2009)
The azo dye Disperse Orange 1 induces DNA damage and cytotoxic effects but does not cause ecotoxic effects in Daphnia similis and Vibrio fischeri
(ELSEVIER SCIENCE BV, 2011)
Azo dyes constitute the largest group of colorants used in industry and can pass through municipal waste water plants nearly unchanged due to their resistance to aerobic treatment, which potentially exposes humans and local ...