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Inhibition of cancer cell growth and migration by dihydroxynaphthyl aryl ketones
(2016)
Dihydroxynaphthyl aryl ketones 1-5 exhibit activity as tubulin polymerization inhibitors by targeting the colchicine binding site of microtubules making them potential anticancer drugs. Therefore, analogues 1-5 have been ...
Effects of cigarette smoke and nicotine on cell viability, migration and myofibroblastic differentiation
(John Wiley & Sons A/S, 2012-02-04)
Background and Objective: Several studies have analysed the role of nicotine as a
prominent agent affecting wound repair in smokers. However, tobacco smoke
contains several components that may alter gingival wound healing. ...
Humoral and cell-mediated immunity in large non-toxic multinodular goitre
(1980-01-01)
Humoral and cell-mediated immunity was investigated in fourteen patients with non-toxic multinodular goitre and ten healthy controls by in vitro methods. These included determination of sheep erythrocyte and complement ...
Atorvastatin increases oxidative stress and inhibits cell migration of oral squamous cell carcinoma in vitro
(2019-03-01)
Objective: This study aimed to evaluate the effect of atorvastatin treatment on reactive oxygen species (ROS) production and tumor angiogenesis in oral squamous cell carcinomas. Material and Methods: An HN13 cell line was ...
Linoleic and oleic acids enhance cell migration by altering the dynamics of microtubules and the remodeling of the actin cytoskeleton at the leading edge
(Nature Publishing Group, 2021-12)
Fatty acids (FA) have a multitude of biological actions on living cells. A target of their action is cell motility, a process of critical importance during cancer cell dissemination. Here, we studied the effect of unsaturated ...
PAI-1 inhibition by simvastatin as a positive adjuvant in cell therapy
(2019-02-01)
Cell therapy (CT) can be briefly described as the use of cells or cell components in the treatment of diseases. One of the main challenges in establishing new cell types for therapy is the low survival rates of homing ...
FMNL1 promotes proliferation and migration of leukemia cells
(Federation Amer Soc Exp BiolBethesdaEUA, 2013)
The heterotrimeric G-protein GEF Ric-8A is involved in the migration of motoneuron-like cells and fibroblasts migration.
(2015)
Introduction. Ric-8A is a highly conserved protein in vertebrates that potentiates heterotrimeric G-protein signaling. This protein is expressed throughout embryonic development in the neural tissue, neural crest (NC) cells ...
Insights into Stem Cell Factor chemotactic guidance of neural crest cells revealed by a real-time directionality-based assay
(Elsevier Gmbh, 2012-05)
The extracellular environment through which neural crest cells (NCCs) translocate and differentiate plays a crucial role in the determination of cell migration and homing. In the trunk, NCC-derived melanocyte precursor ...