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Avaliação da resposta imune celular de sangue periférico e medula óssea pela técnica de imunocitoquímica em cães vacinados para Leishmaniose visceral canina
(Universidade Estadual Paulista (Unesp), 2012-08-14)
O objetivo dessa pesquisa foi analisar a resposta imune celular de cães negativos (GI), vacinados (GII) e positivos (GIII) para a LVC por meio da imunocitoquímica para os anticorpos anti-CD4, anti-CD8 e FOXP3 na capa ...
CD4+CD25highFoxp3+Cells Increased in the Peritoneal Fluid of Patients with Endometriosis
(WILEY-BLACKWELLHOBOKEN, 2012)
Problem To evaluate CD4+CD25highFoxp3+ cells and IL-6, IL-10, IL-17, and TGF-beta in the peritoneal fluid of women with endometriosis. Method of study A total of ninety-eight patients were studied: endometriosis (n = 70) ...
Neutrophil elastase treated dendritic cells promote the generation of CD4+FOXP3+ regulatory T cells in vitro
(Academic Press Inc Elsevier Science, 2011-03)
We have previously shown that neutrophilic elastase converts human immature dendritic cells (DCs) into TGF-β secreting cells and reduces its allostimulatory ability. Since TGF-β has been involved in regulatory T cells ...
Dendritic Cells and B Cells Cooperate in the Generation of CD4+CD25+FOXP3+ Allogeneic T Cells
(2010)
Background: CD4+CD25+Foxp3+ regulatory T cells (Treg) play an essential role in immune tolerance, suppressing responses against self-antigens. Additionally, Treg play an important role in maintaining immunosuppression to ...
CD4+, CD8+ and FOXP3+ lymphocytes infiltrating oral leukoplakia: an immunohistochemical analysis
(Universidade Estadual Paulista (Unesp), 2020-02-07)
Objective: To evaluate the infiltration of CD4+, CD8+ and FOXP3+ lymphocytes and their correlation with sociodemographic, clinicopathological and lifestyle characteristics of patients with oral leukoplakia. Patients and ...
Normalization of FoxP3+ regulatory T cells in response to effective antiretroviral therapy
(Oxford University Press, 2011)
Regulatory T cells (Tregs) blunt uncontrolled immune responses. In advanced human immunodeficiency virus (HIV) infection, the total number of Tregs is decreased, but the proportion of T cells with a regulatory phenotype ...
Thymopoiesis and regulatory T cells in healthy children and adolescents
(HOSPITAL CLINICAS, UNIV SAO PAULOSAO PAULO, 2012)
OBJECTIVES: The purpose of this study was to investigate the association between T cell receptor excision circle levels in peripheral blood mononuclear cells and regulatory T cells that co-express CD25 and Foxp3 in healthy ...