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Diminishing apoptosis by deletion of bax or overexpression of Bcl-2 does not protect against infectious prion toxicity in vivo
(2007)
B-cell lymphoma protein 2 (Bcl-2) and Bcl-2-associated X protein (Bax), key antiapoptotic and proapoptotic proteins, respectively, have important roles in acute and chronic models of neurologic disease. Several studies ...
Bcl-2 and bax Expressions in pre-term, term and post-term placentas
(2008-08-01)
Problem: Placental apoptosis-associated protein imbalance might contribute to the pathogenesis of pre- and post-term birth. Therefore, we evaluated the expression and distribution of pro-apoptotic (Bax) and anti-apoptotic ...
Effect of several PEO-PPO amphiphiles on bax, bcl-2, and hTERT mRNAs: An insight into apoptosis and cell immortalization induced in hepatoma cells by these polymeric excipients
(Wiley, 2016-03)
Recent data have shown that synthetic polymers and nanomaterials display phenotypic effects in cells and signal transduction mechanisms involved in inflammation, differentiation, proliferation, and apoptosis. Aim: This ...
Apoptosis and expression of Bcl-2 and Bax in eutopic endometrium from women with endometriosis
(Elsevier Science Inc, 2000-04)
To evaluate and compare spontaneous apoptosis and Bcl-2 and Bax expression in eutopic endometrium from women with and without endometriosis. Spontaneous apoptosis was significantly lower in eutopic endometrium from patients ...
Phase 3 Clinical Trial: Perioperative Use of Nonacog Gamma, a Recombinant Factor IX, in Previously Treated Patients With Moderate/Severe Hemophilia B
(SAGE, 2020)
Hemostatic management is essential for ensuring the safety of patients with hemophilia during surgery. This phase 3, prospective, uncontrolled trial, evaluated hemostatic efficacy, consumption, and safety of a recombinant ...
Role of nitric oxide and bcl-2 family genes in the regulation of human endometrial apoptosis
(2002)
Objective: To investigate the role of nitric oxide (NO) and death regulatory genes, bcl-2 and bax, in human endometria apoptosis.Design: Expression of bcl-2, bax, NO synthases (NOS), and the apoptotic effect of L-arginine ...
Cigarette smoke affects apoptosis in rat tongue mucosa: Role of bcl-2 gene family
(Springer, 2005-10-01)
While it has been clearly demonstrated that smoking is the most significant exogenous factor involved in oral carcinogenesis, little is known about the global molecular and cellular changes that occur prior to the appearance ...
Cigarette smoke affects apoptosis in rat tongue mucosa: Role of bcl-2 gene family
(Springer, 2005-10-01)
While it has been clearly demonstrated that smoking is the most significant exogenous factor involved in oral carcinogenesis, little is known about the global molecular and cellular changes that occur prior to the appearance ...
Bax and Bcl-2 expression and TUNEL labeling in lumbar enlargement of neonatal rats after sciatic axotomy and melatonin treatment
(Elsevier Science BvAmsterdamHolanda, 2006)