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Biochemical and biophysical properties of a highly active recombinant arginase from Leishmania (Leishmania) amazonensis and subcellular localization of native enzyme
(ELSEVIER SCIENCE BV, 2008)
Arginase (L-arginine amidinohydrolase, E.C. 3.5.3.1) is a metalloenzyme that catalyses the hydrolysis Of L-arginine to L-ornithine and urea. In Leishmania spp., the biological role of the enzyme may be involved in modulating ...
High total cholesterol and triglycerides levels increase arginases metabolism, impairing nitric oxide signaling and worsening fetoplacental endothelial dysfunction in gestational diabetes mellitus pregnancies
(2021-12-01)
Maternal physiological dyslipidemia (MPD) supports fetal development in human pregnancy. However, some women develop maternal supraphysiological dyslipidemia (MSPD: increased total cholesterol (TC) and triglycerides (TG) ...
Crystal structure of escherichia coli agmatinase: Catalytic mechanism and residues relevant for substrate specificity
(MDPI, 2021)
Agmatine is the product of the decarboxylation of L-arginine by the enzyme arginine
decarboxylase. This amine has been attributed to neurotransmitter functions, anticonvulsant, antineurotoxic,
and antidepressant in mammals ...
Host–pathogen interaction between macrophage co-cultures with Staphylococcus aureus biofilms
(Springer, 2021-12)
The ability of Staphylococcus aureus to form biofilms is an important virulence factor. During the infectious process, the interaction between biofilms and immune cells is determinant; however, the properties that make ...
Nitric oxide synthase, arginase and cyclooxygenase are involved in muscarinic receptor activation in different murine mammary adenocarcinoma cell lines
(Spandidos Publications, 2002-06-01)
Investigations on the influence of the parasympathetic nervous system via muscarinic signaling in tumor progression have produced contradictory evidence. We investigated the expression of muscarinic acetylcholine receptors ...
Different Mechanisms Lead to the Angiogenic Process Induced by Three Adenocarcinoma Cell Lines
(Springer, 2004)
Neoangiogenesis is essential for tumor and metastasis growth, but this complex process does not follow the same activation pathway, at least in tumor cell lines originated from different murine mammary adenocarcinomas. ...
Influência da infecção por yersinia pseudotuberculosis sobre o comportamento de macrófagos e células dendríticas
(Universidade Estadual Paulista (Unesp), 2008-07-23)
A infecção por Y. pseudotuberculosis é a causa de doenças intestinais e extraintestinais. A resolução da infecção está relacionada com a ativação de células Th1. Macrófagos e células dendríticas são capazes de orientar a ...
Influência da infecção por yersinia pseudotuberculosis sobre o comportamento de macrófagos e células dendríticas
(Universidade Estadual Paulista (Unesp), 2008-07-23)
A infecção por Y. pseudotuberculosis é a causa de doenças intestinais e extraintestinais. A resolução da infecção está relacionada com a ativação de células Th1. Macrófagos e células dendríticas são capazes de orientar a ...