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Mostrando ítems 31-40 de 108
Efeito dos antagonistas de receptor do tipo 1 de angiotensina II na polimerização da hemoglobina S
(Universidade Federal do Rio de JaneiroBrasilInstituto de Ciências FarmacêuticasUFRJ, 2023)
Telmisartan regresses left ventricular hypertrophy in caveolin-1-deficient mice
(Nature Publishing GroupNew YorkEUA, 2010)
Zinc complexation improves angiotensin II receptor type 1 blockade and in vivo antihypertensive activity of telmisartan
(Future Medicine, 2021-01)
Background: Angiotensin II receptor blockers were designed as therapeutic agents to block the binding site of the angiotensin II receptor type 1 (AT1R). Methodology: The structure of telmisartan was modified by coordination ...
At1 receptor blockade improves myocardial functional performance in obesityBloqueio de Receptores AT1 Melhora o Desempenho Funcional Miocárdico na Obesidade
(2020-07-01)
Background: Obesity has been associated with chronic activation of the renin-angiotensin-aldosterone system and with significant changes in cardiac performance. Objective: To assess the impact of a blockade of angiotensin-II ...
Adição de Bloqueador do receptor de angiotensina II na insuficiência cardíaca descompensada
(Sociedade Brasileira de Cardiologia - SBC, 2010)
FUNDAMENTO: Durante a descompensação da insuficiência cardíaca, ocorre uma intensa ativação do sistema renina-angiotensina-aldosterona, entretanto, o uso de inibidor da enzima de conversão de angiotensina (IECA) não pode ...
The role of local and systemic renin angiotensin system activation in a genetic model of sympathetic hyperactivity-induced heart failure in mice
(AMER PHYSIOLOGICAL SOC, 2008)
Sympathetic hyperactivity (SH) and renin angiotensin system (RAS) activation are commonly associated with heart failure (HF), even though the relative contribution of these factors to the cardiac derangement is less ...
Angiotensin type 1 receptor mediates thyroid hormone-induced cardiomyocyte hypertrophy through the Akt/GSK-3 beta/mTOR signaling pathway
(DR DIETRICH STEINKOPFF VERLAG, 2009)
Several studies have implicated the renin angiotensin system in the cardiac hypertrophy induced by thyroid hormone. However, whether Angiotensin type 1 receptor (AT(1)R) is critically required to the development of ...