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Amyotrophic lateral sclerosis: considerations on diagnostic criteria
(Academia Brasileira de Neurologia - ABNEURO, 2010-12-01)
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder, compromising the motor neuron, characterized by progressive muscle weakness, with reserved prognosis. The diagnosis is based on inclusion and exclusion ...
Nutritional care in motor neurone disease/ amyotrophic lateral sclerosis
(Academia Brasileira de Neurologia - ABNEURO, 2014-02-01)
Patients with amyotrophic lateral sclerosis (ALS) often present changes in nutritional status. Based on weight loss and on difficulty in nutritional management, this study aims to review the different possibilities and to ...
Conjugal amyotrophic lateral sclerosis in Brazil
(Academia Brasileira de Neurologia - ABNEURO, 2009-12-01)
The origin of amyotrophic lateral sclerosis (ALS) remains unknown, although it seems to be multifactorial. The role of environmental factors has been frequently investigated and suspicion of its influence can be obtained ...
Magnetic resonance findings in amyotrophic lateral sclerosis using a spin echo magnetization transfer sequence: preliminary report
(Academia Brasileira de Neurologia - ABNEURO, 1999-12-01)
We present the magnetic resonance (MR) findings of five patients with amyotrophic lateral sclerosis (ALS) using a spin-echo sequence with an additional magnetization transfer (MT) pulse on T1-weighted images (T1 SE/MT). ...
Effect of amyotrophic lateral sclerosis serum on calcium channels related to spontaneous acetylcholine release
(Elsevier Ireland, 2002-12)
Objectives: The aim of this work was to further investigate the effect of sera from sporadic amyotrophic lateral sclerosis (ALS) patients on miniature end-plate potentials (MEPP) frequency, by the mouse passive transfer ...
Circulating gonadal and adrenal steroids in amyotrophic lateral sclerosis: possible markers of susceptibility and outcome
(Georg Thieme Verlag Kg, 2014-05-07)
Although changes of circulating steroids have been reported in patients with sporadic amyotrophic lateral sclerosis (ALS), a full comparison of the adrenal and gonadal steroid profile between control subjects and ALS ...
Expression and cellular localization of the classical progesterone receptor in healthy and amyotrophic lateral sclerosis affected spinal cord
(Wiley, 2014-02)
Background and purpose
Previous studies have suggested that elevated progesterone levels are associated with a slower disease course in amyotrophic lateral sclerosis (ALS). Given that the effects of progesterone are ...
Progesterone and Allopregnanolone Neuroprotective Effects in the Wobbler Mouse Model of Amyotrophic Lateral Sclerosis
(Springer/Plenum Publishers, 2021-06)
Progesterone regulates a number of processes in neurons and glial cells not directly involved in reproduction or sex behavior. Several neuroprotective effects are better observed under pathological conditions, as shown in ...